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It is generally well tolerated with few significant side effects. [1] Side effects may include irregular menstrual periods, no periods, headaches, and breast pain. [3] [4] Use is not recommended in people with significant liver disease. [3] The levonorgestrel implant is a type of long-acting reversible birth control. [5]
A levonorgestrel-releasing implant is also available in some countries. [12] Common side effects include nausea, breast tenderness, headaches, and increased, decreased, or irregular menstrual bleeding. [7] When used as an emergency contraceptive, if pregnancy occurs, there is no evidence that its use harms the fetus. [7]
In comparison, oral contraceptives can contain 150 micrograms of levonorgestrel. [53] The hormonal IUD releases the levonorgestrel directly into the uterus, as such its effects are mostly paracrine rather than systemic. Most of the drug stays inside the uterus, and only a small amount is absorbed into the rest of the body. [53]
The etonogestrel implant, also called the contraceptive implant, or known by trade names Nexplanon or Implanon is one type of progestin-releasing birth control device implanted under the skin. It is approved for up to three years of use, but may be effective for up to five years.
For some users, these side effects lead them to discontinue use. [23] The most common side effect of the contraceptive implant is irregular bleeding, which includes both reduced and increased levels of bleeding. [24] Other side effects include mood changes and mild insulin resistance. [21]
A contraceptive implant is an implantable medical device used for the purpose of birth control.The implant may depend on the timed release of hormones to hinder ovulation or sperm development, the ability of copper to act as a natural spermicide within the uterus, or it may work using a non-hormonal, physical blocking mechanism.
It is less androgenic than levonorgestrel and norethisterone, [48] [49] and it does not cause a decrease in sex hormone-binding globulin levels. [50] However, it is still associated with acne in up to 13.5% of patients when used as an implant, though this side effect only accounts for 1.3% of premature removals of the implant. [51]
Side effects can include nausea, headache, blood clots, breast pain, depression, and liver problems. [3] Use is not recommended during pregnancy, the initial three weeks after childbirth, and in those at high risk of blood clots. [3] However, it may be started immediately after a miscarriage or abortion. [5]
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