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  2. Haemophilia - Wikipedia

    en.wikipedia.org/wiki/Haemophilia

    Like most aspects of the disorder, life expectancy varies with severity and adequate treatment. People with severe haemophilia who do not receive adequate, modern treatment have greatly shortened lifespans and often do not reach maturity. Prior to the 1960s when effective treatment became available, average life expectancy was only 11 years. [21]

  3. Fibrodysplasia ossificans progressiva - Wikipedia

    en.wikipedia.org/wiki/Fibrodysplasia_ossificans...

    Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).

  4. Acquired haemophilia - Wikipedia

    en.wikipedia.org/wiki/Acquired_haemophilia

    Acquired haemophilia A (AHA) is a rare but potentially life-threatening bleeding disorder characterized by autoantibodies directed against coagulation factor VIII.These autoantibodies constitute the most common spontaneous inhibitor to any coagulation factor and may induce spontaneous bleeding in patients with no previous history of a bleeding disorder.

  5. List of countries by past life expectancy - Wikipedia

    en.wikipedia.org/wiki/List_of_countries_by_past...

    Life expectancy by world region, from 1770 to 2018. This is a list of countries showing past life expectancy, ranging from 1950 to 2015 in five-year periods, as estimated by the 2017 revision of the World Population Prospects database by the United Nations Population Division. Life expectancy equals the average number of years a person born in ...

  6. Haemophilia B - Wikipedia

    en.wikipedia.org/wiki/Haemophilia_B

    X chromosome. The factor IX gene is located on the X chromosome (Xq27.1-q27.2). It is an X-linked recessive trait, which explains why males are affected in greater numbers. [9] [10] A change in the F9 gene, which makes blood clotting factor IX (9), causes haemophilia B. [11]

  7. Fall in life expectancy for men and women in UK driven by ...

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  8. Haemophilia A - Wikipedia

    en.wikipedia.org/wiki/Haemophilia_A

    Joint capsule. Haemophilia A's phenotype has a quite wide range of symptoms encompassing both internal and external bleeding episodes. Individuals with more severe haemophilia tend to experience more intense and frequent bleeding, whereas those with mild haemophilia typically exhibit milder symptoms unless subjected to surgical procedures or significant trauma.

  9. Hereditary haemochromatosis - Wikipedia

    en.wikipedia.org/wiki/Hereditary_haemochromatosis

    Haemochromatosis is protean in its manifestations, i.e., often presenting with signs or symptoms suggestive of other diagnoses that affect specific organ systems.Many of the signs and symptoms below are uncommon, and most patients with the hereditary form of haemochromatosis do not show any overt signs of disease nor do they have premature morbidity, if they are diagnosed early, but, more ...

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