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  2. False discovery rate - Wikipedia

    en.wikipedia.org/wiki/False_discovery_rate

    FCR indicates the average rate of false coverage, namely, not covering the true parameters, among the selected intervals. The FCR gives a simultaneous coverage at a level for all of the parameters considered in the problem. Intervals with simultaneous coverage probability 1−q can control the FCR to be bounded by q.

  3. p-value - Wikipedia

    en.wikipedia.org/wiki/P-value

    In null-hypothesis significance testing, the p-value [note 1] is the probability of obtaining test results at least as extreme as the result actually observed, under the assumption that the null hypothesis is correct.

  4. Statistical significance - Wikipedia

    en.wikipedia.org/wiki/Statistical_significance

    Statistical significance dates to the 18th century, in the work of John Arbuthnot and Pierre-Simon Laplace, who computed the p-value for the human sex ratio at birth, assuming a null hypothesis of equal probability of male and female births; see p-value § History for details.

  5. Effect size - Wikipedia

    en.wikipedia.org/wiki/Effect_size

    In statistics, an effect size is a value measuring the strength of the relationship between two variables in a population, or a sample-based estimate of that quantity. It can refer to the value of a statistic calculated from a sample of data, the value of one parameter for a hypothetical population, or to the equation that operationalizes how statistics or parameters lead to the effect size ...

  6. Minor allele frequency - Wikipedia

    en.wikipedia.org/wiki/Minor_allele_frequency

    1. Introduce the reference of a SNP of interest, as an example: rs429358, in a database (dbSNP or other). 2. Find MAF/MinorAlleleCount link. MAF/MinorAlleleCount: C=0.1506/754 (1000 Genomes, where number of genomes sampled = N = 2504); [4] where C is the minor allele for that particular locus; 0.1506 is the frequency of the C allele (MAF), i.e. 15% within the 1000 Genomes database; and 754 is ...

  7. Accuracy and precision - Wikipedia

    en.wikipedia.org/wiki/Accuracy_and_precision

    Accuracy is also used as a statistical measure of how well a binary classification test correctly identifies or excludes a condition. That is, the accuracy is the proportion of correct predictions (both true positives and true negatives) among the total number of cases examined. [10]

  8. Likert scale - Wikipedia

    en.wikipedia.org/wiki/Likert_scale

    A Likert scale (/ ˈ l ɪ k ər t / LIK-ərt, [1] [note 1]) is a psychometric scale named after its inventor, American social psychologist Rensis Likert, [2] which is commonly used in research questionnaires.

  9. Allosteric regulation - Wikipedia

    en.wikipedia.org/wiki/Allosteric_regulation

    Allosteric regulation of an enzyme. In the fields of biochemistry and pharmacology an allosteric regulator (or allosteric modulator) is a substance that binds to a site on an enzyme or receptor distinct from the active site, resulting in a conformational change that alters the protein's activity, either enhancing or inhibiting its function.

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