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The Parkinson's Disease Foundation is a leading national presence in the United States in Parkinson's disease research, education and public advocacy. PDF works on behalf of people who live with Parkinson's disease by funding promising clinical research to find treatments and cures for Parkinson's. [ 30 ]
The unified Parkinson's disease rating scale (UPDRS) is used to follow the longitudinal course of Parkinson's disease. The UPD rating scale is the most commonly used scale in the clinical study of Parkinson's disease. [1] The UPDRS is made up of these sections: [2] Part I: evaluation of mentation, behavior, and mood
Biomarkers identification and validation: The Lashuel group is a member of several international consortia which aim to develop novel therapies for the treatment of neurodegenerative diseases and to identify biomarkers for improving diagnosis, monitoring disease progression and establishing target engagement in clinical trials.
The Parkinson's Foundation Research Advocates program trains Parkinson's patients and their caregivers to collaborate with Parkinson's disease scientists in research. [ 39 ] [ 40 ] The program was established in 2008 and has trained more than 350 participants.
Parkinsonism is a clinical syndrome characterized by the four motor symptoms found in Parkinson's disease: tremor, bradykinesia (slowed movements), rigidity, and postural instability. [ 1 ] [ 2 ] Parkinsonism gait problems can lead to falls and serious physical injuries.
In Parkinson's disease (PD), for example, finger tapping a mobile phone via counting apps have been used as a method of (self-)evaluating bradykinesia and effectiveness of medication. [16] Digital biomarkers are currently being used in conjugation with artificial intelligence (A.I.) in order to recognize symptoms for mild cognitive impairment ...
In the management of Parkinson's disease, due to the chronic nature of Parkinson's disease (PD), a broad-based program is needed that includes patient and family education, support-group services, general wellness maintenance, exercise, and nutrition. At present, no cure for the disease is known, but medications or surgery can provide relief ...
Biomarker discovery is a medical term describing the process by which biomarkers are discovered. Many commonly used blood tests in medicine are biomarkers. There is interest in biomarker discovery on the part of the pharmaceutical industry; blood-test or other biomarkers could serve as intermediate markers of disease in clinical trials, and as possible drug targets.
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