Search results
Results from the WOW.Com Content Network
While liposarcoma forms are classified as being aggressive and malignant or, in the case of the atypical lipomatous tumor/well-differentiated liposarcoma, as relatively non-aggressive and benign, [6] all five liposarcoma forms can infiltrate locally to injure nearby tissues and organs, occur in surgically inaccessible sites adjacent to vital ...
Histopathology of liposarcoma, H&E stain, with the main features: [5] - Spindle cells with enlarged, hyperchromatic nuclei. - Apparently univacuolated adipocytes (may look normal). - Lipoblasts (multivacuolated), but neither necessary nor sufficient for diagnosis of liposarcoma.
Undifferentiated pleomorphic sarcoma (UPS), also termed pleomorphic myofibrosarcoma, [1] high-grade myofibroblastic sarcoma, and high-grade myofibrosarcoma, [2] is characterized by the World Health Organization (WHO) as a rare, poorly differentiated neoplasm (i.e., an abnormal growth of cells that have an unclear identity and/or cell of origin). [3]
A myxoid liposarcoma is a malignant adipose tissue neoplasm [1] of myxoid appearance histologically.. Myxoid liposarcomas are the second-most common type of liposarcoma, representing 30–40% of all liposarcomas in the limbs, occurring most commonly in the legs, particularly the thigh, followed by the buttocks, retroperitoneum, trunk, ankle, proximal limb girdle, head and neck, and wrist.
Histopathology of the major differential diagnosis of a well-differentiated liposarcoma, lipoma-like subtype: It looks almost identical at low magnification, but a high magnification of a fibrous band shows spindle cells with enlarged, hyperchromatic nuclei. H&E stain.
Fibroblastic and myofibroblastic tumors (FMTs) are tumors which develop from the mesenchymal stem cells which differentiate into fibroblasts (the most common cell type in connective tissue) and/or the myocytes/myoblasts that differentiate into muscle cells.
At least one case of FIP1L1-PDGFRA fusion gene-induced eosinophilic leukemia presenting with myeloid sarcoma and eosinophilia has been reported. This form of myeloid sarcoma is distinguished by its highly successful treatment with imatinib (the recommended treatment for FIP1L1-PDGRGA fusion gene-induced eosinophilic leukemia) rather than more aggressive and toxic therapy.
Touton giant cells are considered white blood cells due to their role in the immune system as well as where they are derived from. These multinucleated giant cells are formed by the fusion of macrophages, a type of white blood cell that has many functions such as removing dead cells and stimulating the action of other immune cells.