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Since lipase inhibitors are not absorbed in the intestine, and consequently not circulating in the blood, information about alternative side effects such as the modulation [clarification needed] of the gastrointestinal tract is unobtainable. [1] Generally, side effects can be controlled by reducing the consumption of dietary fats.
Orlistat, sold under the brand name Xenical among others, is a medication used to treat obesity.Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake.
The most common side effects of these drugs that led to withdrawals were mental disturbances, cardiac side effects, and drug abuse or drug dependence. Deaths were associated with seven products. [84] Ephedra was removed from the US market in 2004 over concerns that it raises blood pressure and could lead to strokes and death. [85]
Cetilistat is a drug designed to treat obesity.It acts in the same way as the older drug orlistat (Xenical) by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine.
Other lipase inhibitors have been recognized, e.g. from different plant products. These include alkaloids, carotenoids, glycosides, polyphenols, polysaccharides, saponins and terpenoids. However, none of these have been used clinically as lipase inhibitors. More active lipase inhibitors are the lipophilic compounds from microbial sources. [4]
A combination therapy of two drugs — a statin and a protein inhibitor — may help suppress the creation and growth of tumors in bladder cancer, a new study finds. Reducing cholesterol may help ...
A study confirmed that side effects like pancreatitis and kidney damage are possible while taking GLP-1s like Ozempic. Here's what a doctor wants you to know.
Common side effects include headache, dizziness, feeling tired, and intestinal upset. [3] Serious side effects may include angioedema, gallstones, liver problems, and muscle breakdown. [3] Use in pregnancy and breastfeeding is of unclear safety. [5] It belongs to the fibrates group of medications and works by decreasing the breakdown of lipids ...