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Bitot's spots are the buildup of keratin located superficially in the conjunctiva of human's eyes. They can be oval, triangular or irregular in shape. The spots are a sign of vitamin A deficiency and associated with drying of the cornea. In 1863, the French physician Pierre Bitot (1822–1888) first described these spots. [1]
The corneal limbus is the border between the cornea and the sclera. [1] It is highly vascularised. [1] Its stratified squamous epithelium is continuous with the epithelium covering the cornea. [2] The corneal limbus contains radially-oriented fibrovascular ridges known as the palisades of Vogt that contain limbal stem cells.
Roth's spots, also known as Litten spots or the Litten sign, [1] are non-specific red lesions with white or pale centres, seen on the retina of the eye and although traditionally associated with infective endocarditis, can occur in a number of other conditions including hypertension, diabetes, collagen vascular disease, extreme hypoxia, leukemia and HIV.
Multiple evanescent white dot syndrome occurs mostly in females. Symptoms include a sudden loss of central vision, but patients eventually regain normal vision. The white dots are small and located in the posterior pole at the level of the retinal pigment epithelium. The white dots may disappear after the first few weeks of the disease.
Colour, where the retina is illuminated by white light and examined in full colour. Red free fundus photography utilizes a filter in order to better observe superficial lesions and some vascular abnormalities within the retina and surrounding tissue. A green filter ~540–570 nm is used to block out red wavelengths of light.
Uveitis (/ ˌ juː v i. aɪ t ɪ s /) is inflammation of the uvea, the pigmented layer of the eye between the inner retina and the outer fibrous layer composed of the sclera and cornea. [1] The uvea consists of the middle layer of pigmented vascular structures of the eye and includes the iris , ciliary body , and choroid .
Purkinje images are reflections of objects from the structure of the eye. They are also known as Purkinje reflexes and as Purkinje–Sanson images. At least four Purkinje images are usually visible in the normal eye. The first Purkinje image (P1) is the reflection from the outer surface of the cornea. The second Purkinje image (P2) is the ...
Cotton wool spots are typically a sign of another disease state, most common of which is diabetic retinopathy. [2] The irregularly shaped white patches are a result of ischemia, or reduced blood flow and oxygen, in the retinal nerve fiber layer, which is located in the distribution of the capillaries of the superficial layer of the retina. [2]