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[2] [3] [4] Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower (0.2–0.3 mg/kg or 10 to 15 mg for a 50 kg person) than lethal doses. [5] Although it is helpful topically for dental health in low dosage, chronic ingestion of fluoride in large amounts interferes with bone formation.
Sensodyne is a brand of toothpaste that was first sold by Block Drug, a Brooklyn, New York-based company established in 1907 by pharmacist Alexander Block. [1]By 1925, manufacturing dental care products had become the company's focus.
Whitening toothpaste According to a 2018 study , chemical teeth-whitening toothpaste outperforms natural alternatives. Despite this, it isn't as highly recommended as whitening strips or trays.
Topical fluorides are fluoride-containing drugs indicated in prevention and treatment of dental caries, particularly in children's primary dentitions. [1] The dental-protecting property of topical fluoride can be attributed to multiple mechanisms of action, including the promotion of remineralization of decalcified enamel, the inhibition of the cariogenic microbial metabolism in dental plaque ...
Fluoride toothpaste, with concentrations of 1000 ppm and above, reduces the risk of dental caries in school-aged children and adolescents. [10] As primary teeth are being developed, the ingestion of fluoride causes the teeth to form stronger and more resistant to cavities, although this increases the risk of dental fluorosis.
The additional fluoride in toothpaste has beneficial effects on the formation of dental enamel and bones. Sodium fluoride (NaF) is the most common source of fluoride, but stannous fluoride (SnF 2 ), and sodium monofluorophosphate (Na 2 PO 3 F) are also used. [ 12 ]
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