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RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre- mRNA) transcript is transformed into a mature messenger RNA (mRNA). It works by removing all the introns (non-coding regions of RNA) and splicing back together exons (coding regions).
RNA splicing is a form of RNA processing in which a newly made precursor messenger RNA (mRNA) is transformed into a mature RNA by removing the non-coding sequences termed introns. The process of RNA splicing involves the removal of non-coding sequences or introns and joining of the coding sequences or exons.
Before mRNA is used as instructions to make a protein, it can be cut into smaller sections and re-arranged in a process called splicing. Splicing occurs at the end of the transcription process, as part of pre-mRNA processing.
What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms.
RNA splicing is the process by which the removal of noncoding intronic sequences from a pre-mRNA is paired with the ligation of coding exons to generate a mature mRNA transcript [3] (Box 1).
Splicing is the process of removing the introns from the pre-MRNA and linking the exons together. It occurs in the nucleus prior to the export of mature MRNA into the cytoplasm. In the majority of genes, protein-coding information is interrupted by noncoding sections known as “introns.”
RNA splicing is a complex and dynamic process by which protein coding sequences (exons), split within the genome by intervening non-coding regions (introns), are reconstituted into a continuous, mature mRNA molecule by the macromolecular complex known as the spliceosome.