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Hydroxyethyl starch (HES/HAES), sold under the brand name Voluven among others, is a nonionic starch derivative, used as a volume expander in intravenous therapy. The use of HES on critically ill patients is associated with an increased risk of death and kidney problems.
Volume expander. A volume expander is a type of intravenous therapy that has the function of providing volume for the circulatory system. It may be used for fluid replacement or during surgery to prevent nausea and vomiting after surgery. [1]
Pentastarch is a subgroup of hydroxyethyl starch, with five hydroxyethyl groups out of each 11 hydroxyls, giving it approximately 50% hydroxyethylation. This compares with tetrastarch at 40% and hetastarch at 70% hydroxyethylation, respectively. It is sold under the name Pentaspan and used for fluid resuscitation.
He was an advocate for the use of colloidal hydroxyethyl starch (HES) to boost blood pressure during surgery. [3] However, a meta-analysis of trials that excluded Boldt's fabricated data found that the intravenous use of hydroxyethyl starch is associated with a significant increased risk of death and acute kidney injury compared with other ...
Specialty. Dermatology. Hydroxyethyl starch-induced pruritus is an intense itching, lasting for as long as one year, occurring following hydroxyethyl starch intravenous infusion for vascular insufficiency. [1] [2] : 401.
Intravenous ascorbic acid. Intravenous sodium bicarbonate. Intravenous sugar solution. Intravenous therapy.
Sepsis is a potentially life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. [4][7] This initial stage of sepsis is followed by suppression of the immune system. [8] Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. [1]
Cerebral edema is excess accumulation of fluid (edema) in the intracellular or extracellular spaces of the brain. [1] This typically causes impaired nerve function, increased pressure within the skull, and can eventually lead to direct compression of brain tissue and blood vessels. [1] Symptoms vary based on the location and extent of edema and ...