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ABO blood group antigens present on red blood cells and IgM antibodies present in the serum. The ABO blood group system is used to denote the presence of one, both, or neither of the A and B antigens on erythrocytes (red blood cells). [1] For human blood transfusions, it is the most important of the 44 different blood type (or group ...
Blood type (or blood group) is determined, in part, by the ABO blood group antigens present on red blood cells. A blood type (also known as a blood group) is a classification of blood, based on the presence and absence of antibodies and inherited antigenic substances on the surface of red blood cells (RBCs).
The term human blood group systems is defined by the International Society of Blood Transfusion (ISBT) as systems in the human species where cell-surface antigens—in particular, those on blood cells—are "controlled at a single gene locus or by two or more very closely linked homologous genes with little or no observable recombination between them", [1] and include the common ABO and Rh ...
ABO antigens and antibodies. Blood types are defined according to the presence or absence of specific antigens on the surface of red blood cells. The most important of these in medicine are the ABO and RhD antigens [7]: 585 but many other blood group systems exist and may be clinically relevant in some situations.
ABO (gene) Histo-blood group ABO system transferase is an enzyme with glycosyltransferase activity, which is encoded by the ABO gene in humans. [5][6] It is ubiquitously expressed in many tissues and cell types. [7] ABO determines the ABO blood group of an individual by modifying the oligosaccharides on cell surface glycoproteins.
The H antigen is required for ABO blood group antigens to be formed. [note 1] The Se gene, which encodes the enzyme α-2-L-fucosyltransferase, controls the formation of H antigen in bodily secretions. In people with the secretor genotype, the enzyme converts a precursor substance found in body fluids to the H antigen, which is then modified by ...
The Lewis antigen system is a human blood group system. It is based upon two genes on chromosome 19: FUT3, or Lewis gene; and FUT2, or Secretor gene. Both genes are expressed in glandular epithelia. FUT2 has a dominant allele which codes for an enzyme (designated Se) and a recessive allele which does not produce a functional enzyme (designated se).
The Rh blood group system is a human blood group system. It contains proteins on the surface of red blood cells. After the ABO blood group system, it is the most likely to be involved in transfusion reactions. The Rh blood group system consisted of 49 defined blood group antigens [1] in 2005. As of 2023, there are over 50 antigens among which ...
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