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Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs ...
ACS Medicinal Chemistry Letters is a monthly peer-reviewed scientific journal covering medicinal chemistry. It was established in 2009 and is published by the American Chemical Society. The editor-in-chief is Dennis C. Liotta (Emory University). According to the Journal Citation Reports, the journal has a 2021 impact factor of 4.632.
Products. Medical and surgical supplies. Revenue. US$ $21.2 billion (2022) [ 1 ] Number of employees. 36,000 (2023) [ 1 ] Website. www.medline.com. Medline Industries, LP is an American private healthcare company headquartered in Northfield, Illinois.
In medicinal chemistry, parallel artificial membrane permeability assay (PAMPA) is a method which determines the permeability of substances from a donor compartment, through a lipid -infused artificial membrane into an acceptor compartment. [1] A multi-well microtitre plate is used for the donor and a membrane/acceptor compartment is placed on ...
Chemistry. [edit] Fulvestrant, also known as 7α- [9- [ (4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]estradiol, is a synthetic estrane steroid and a derivative of estradiol. An alkyl - sulfinyl moiety was added to the endogenous estrogen receptor ligand. [ 6 ] It was discovered through rational drug design, but was selected for further ...
Cenicriviroc (INN, [ 1 ] code names TAK-652, TBR-652, commonly abbreviated as CVC) is an experimental drug candidate for the treatment of HIV infection [ 2 ] and in combination with Tropifexor for non-alcoholic steatohepatitis. [ 3 ] It is being developed by Takeda and Tobira Therapeutics. [citation needed]
Molecular Pharmaceutics. Molecular Pharmaceutics is a peer-reviewed scientific journal covering research on the molecular mechanistic understanding of drug delivery and drug delivery systems, including physical and pharmaceutical chemistry, biochemistry and biophysics, molecular and cellular biology, and polymer and materials science.
PubChem. PubChem is a database of chemical molecules and their activities against biological assays. The system is maintained by the National Center for Biotechnology Information (NCBI), a component of the National Library of Medicine, which is part of the United States National Institutes of Health (NIH).