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  2. Etoposide - Wikipedia

    en.wikipedia.org/wiki/Etoposide

    Etoposide, sold under the brand name Vepesid among others, is a chemotherapy medication used for the treatments of a number of types of cancer including testicular cancer, lung cancer, lymphoma, leukemia, neuroblastoma, and ovarian cancer. [2] It is also used for hemophagocytic lymphohistiocytosis. [3] It is used by mouth or injection into a ...

  3. Epipodophyllotoxin - Wikipedia

    en.wikipedia.org/wiki/Epipodophyllotoxin

    Etoposide, an epipodophyllotoxin. Epipodophyllotoxins are substances naturally occurring in the root of American Mayapple plant (Podophyllum peltatum). Some epipodophyllotoxin derivatives are currently used in the treatment of cancer. These include etoposide and teniposide. They act as anti-cancer drugs by inhibiting topoisomerase II. [1]

  4. List of chemotherapeutic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_chemotherapeutic...

    This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer.This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision.

  5. Topoisomerase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Topoisomerase_inhibitor

    Etoposide is a highly schedule-dependent drug and is typically administered orally and recommended to take twice the dosage for effective treatment. [ 13 ] [ 68 ] However, with the selective dosage, etoposide treatment is dose limiting proposing toxic effects like myelosupression (leukopenia) and primarily hematologic.

  6. Plant sources of anti-cancer agents - Wikipedia

    en.wikipedia.org/wiki/Plant_sources_of_anti...

    Extracts from Camptotheca (the "happy tree" or "cancer tree") were used to develop the chemotherapeutic drug Topotecan. Plant sources of anti-cancer agents are plants, the derivatives of which have been shown to be usable for the treatment or prevention of cancer in humans. [1] [2]

  7. Podophyllotoxin - Wikipedia

    en.wikipedia.org/wiki/Podophyllotoxin

    Podophyllotoxin derived antitumor agents include etoposide and teniposide. [10] [37] These drugs have been successfully used in therapy against numerous cancers including testicular, breast, pancreatic, lung, stomach, and ovarian cancers. [32] Derivatives of podophyllotoxin that have been engineered for their ability to fight tumors. [38]

  8. Chemotherapy - Wikipedia

    en.wikipedia.org/wiki/Chemotherapy

    As most chemotherapy drugs kill cancer cells in this manner, defective apoptosis allows survival of these cells, making them resistant. Many chemotherapy drugs also cause DNA damage, which can be repaired by enzymes in the cell that carry out DNA repair. Upregulation of these genes can overcome the DNA damage and prevent the induction of apoptosis.

  9. Teniposide - Wikipedia

    en.wikipedia.org/wiki/Teniposide

    Teniposide (trade name Vumon) is a chemotherapeutic medication [1] used in the treatment of childhood acute lymphocytic leukemia (ALL), Hodgkin's lymphoma, certain brain tumours, and other types of cancer. [2] It is in a class of drugs known as podophyllotoxin derivatives and slows the growth of cancer cells in the body. [3]

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