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A cannabis edible, also known as a cannabis-infused food or simply an edible, is a food item (either homemade or produced commercially) that contains decarboxylated cannabinoids (cannabinoid acids converted to their orally bioactive form) from cannabis extract as an active ingredient. [1]
The subject expert committee of CDSCO has recommended the grant of permission for manufacturing and marketing of Desidustat 25 mg and 50 mg tablets in India, based on some conditions related to package insert, phase 4 protocols, prescription details, and GCP. [3] Clinical trials on desidustat have been done in India and Australia. [4]
Concentration-response curves illustrating the concept of potency. For a response of 0.25a.u., Drug B is more potent, as it generates this response at a lower concentration.
For example, in 2010, nine people died due to the combination of O-desmethyltramadol, a μ-opioid agonist and analgesic drug, and kratom, an Asiatic medicinal plant containing mitragynine, another μ-opioid agonist, in a synthetic cannabinoid product called "Krypton". [38] And in 2013, AH-7921 was detected in smoking blends in Japan. [39]
For example, a 2017 analysis of cannabidiol content in oil, tincture, or liquid vape products purchased online in the United States showed that 69% were mislabeled, with 43% having higher and 26% having lower content than stated on product labels. [100] [57] In 2020, the FDA conducted a study of 147 CBD products and found that half contained THC.
For example, “older people have higher risk for cognitive vulnerability at baseline and they metabolize many drugs including THC differently than younger people because of their body composition ...
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[27] [28] An average cigarette yields about 2 mg of absorbed nicotine. [29] The estimated lower dose limit for fatal outcomes is 500–1,000 mg of ingested nicotine for an adult (6.5–13 mg/kg). [ 27 ] [ 29 ] Nicotine addiction involves drug-reinforced behavior, compulsive use, and relapse following abstinence. [ 30 ]