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The Mayo Clinic diet was created by weight management practitioners at the Mayo Clinic and was designed as a lifestyle change program to promote gradual and sustained weight loss, says Melissa ...
The Mayo Clinic has disavowed the grapefruit diet. [4] Novelist Fannie Hurst was a notable devotee of the diet. [5] It was re-popularized in the 1980s and nicknamed the "10-day, 10-pounds-off diet". [6] The idea that grapefruit eaten before a meal acts as a "catalyst" to burn body fat has no evidence from biochemistry. [6]
Ciclosporin (cyclosporine, Neoral): Blood levels of ciclosporin are increased if taken with grapefruit juice, orange juice, or apple juice. [12] A plausible mechanism involves the combined inhibition of enteric CYP3A4 and MDR1, which potentially leads to serious adverse events (e.g., nephrotoxicity).
The legitimate Mayo Clinic Diet does not promote a high protein or "key food" approach. There have been diets falsely attributed to Mayo Clinic for decades. [ 3 ] Many or most web sites claiming to debunk the bogus version of the diet are actually promoting it or a similar fad diet.
The Health Benefits Of Grapefruit. Water-rich grapefruit contains a variety of nutrients that your body needs. One cup of grapefruit contains over 100% of your daily vitamin C, in addition to ...
The Mayo Clinic diet is consistently ranked as one of the best diets according to U.S New and World Report's rankings, coming in fourth for the overall best diet in the 2022 rankings.
Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]
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