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The human body needs iron for oxygen transport. Oxygen (O 2) is required for the functioning and survival of nearly all cell types. Oxygen is transported from the lungs to the rest of the body bound to the heme group of hemoglobin in red blood cells. In muscles cells, iron binds oxygen to myoglobin, which regulates its release.
Haematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent haematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. [ 10 ] [ 11 ] [ 12 ] It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an ...
Ferrochrome or ferrochromium (FeCr) is a type of ferroalloy, that is, an alloy of chromium and iron, generally containing 50 to 70% chromium by weight. [ 1 ] [ 2 ] Ferrochrome is produced by electric arc carbothermic reduction of chromite .
When blood leaves a ruptured blood vessel, the red blood cell dies, and the hemoglobin of the cell is released into the extracellular space. Phagocytic cells (of the mononuclear phagocyte system) called macrophages engulf (phagocytose) the hemoglobin to degrade it, producing hemosiderin and biliverdin. Excessive systemic accumulations of ...
The production of siderophores also requires the bacterium to expend energy. Thus, siderophore production can be looked at as an altruistic trait because it is beneficial for the local group but costly for the individual. This altruistic dynamic requires every member of the cellular population to equally contribute to siderophore production.
One major trigger for the production of many ferritins is the mere presence of iron; [9] an exception is the yolk ferritin of Lymnaea sp., which lacks an iron-responsive unit. [12] Free iron is toxic to cells as it acts as a catalyst in the formation of free radicals from reactive oxygen species via the Fenton reaction. [17]
The hepatocyte is a cell in the body that manufactures serum albumin, fibrinogen, and the prothrombin group of clotting factors (except for Factors 3 and 4). [ citation needed ] It is the main site for the synthesis of lipoproteins , ceruloplasmin , transferrin , complement , and glycoproteins .
Iron deficiency, or sideropenia, is the state in which a body lacks enough iron to supply its needs. Iron is present in all cells in the human body and has several vital functions, such as carrying oxygen to the tissues from the lungs as a key component of the hemoglobin protein, acting as a transport medium for electrons within the cells in the form of cytochromes, and facilitating oxygen ...