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Cyanocobalamin is a form of vitamin B 12 used to treat and prevent vitamin B 12 deficiency except in the presence of cyanide toxicity. [7] [8] [2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer.
Vitamin B 12 deficiency; Other names: Hypocobalaminemia, cobalamin deficiency: Image of the cervical spinal cord in vitamin B 12 deficiency showing subacute combined degeneration. . (A) The midsagittal T2 weighted image shows linear hyperintensity in the posterior portion of the cervical tract of the spinal cord (black arrow
"B12" and "Cbl" redirect here. For other uses of B12, see B12 (disambiguation). For the musical group, see Carbon Based Lifeforms. Pharmaceutical compound Vitamin B12 General skeletal formula of cobalamins Stick model of cyanocobalamin (R = CN) based on the crystal structure Clinical data Other names Vitamin B12, vitamin B-12, cobalamin AHFS / Drugs.com Monograph MedlinePlus a605007 License ...
Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [5] The most common initial symptoms are feeling tired and weak. [4]
Hydroxocobalamin has a higher affinity to the TC II transport protein than cyanocobalamin, or adenosylcobalamin. From a biochemical point of view, two essential enzymatic reactions require vitamin B 12 (cobalamin). [21] [22] Intracellular vitamin B 12 is maintained in two active coenzymes, methylcobalamin and adenosylcobalamin.
A nursing diagnosis may be part of the nursing process and is a clinical judgment about individual, family, or community experiences/responses to actual or potential health problems/life processes. Nursing diagnoses foster the nurse's independent practice (e.g., patient comfort or relief) compared to dependent interventions driven by physician ...
Hydroxocobalamin, a form (or vitamer) of vitamin B 12 made by bacteria, and sometimes denoted vitamin B 12a, is used to bind cyanide to form the harmless cyanocobalamin form of vitamin B 12. 4-Dimethylaminophenol: 4-Dimethylaminophenol (4-DMAP) has been proposed [by whom?] in Germany as a more rapid antidote than nitrites with (reportedly ...
In enzymology, a cyanocobalamin reductase (cyanide-eliminating) (EC 1.16.1.6) is an enzyme that catalyzes the chemical reaction cob(I)alamin + cyanide + NADP + ⇌ {\displaystyle \rightleftharpoons } cyanocob(III)alamin + NADPH + H +
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