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  2. Myosin head - Wikipedia

    en.wikipedia.org/wiki/Myosin_head

    The myosin head is the part of the thick myofilament made up of myosin that acts in muscle contraction, by sliding over thin myofilaments of actin.Myosin is the major component of the thick filaments and most myosin molecules are composed of a head, neck, and tail domain; the myosin head binds to thin filamentous actin, and uses ATP hydrolysis to generate force and "walk" along the thin filament.

  3. MYH7 - Wikipedia

    en.wikipedia.org/wiki/MYH7

    MHC-β is a 223 kDa protein composed of 1935 amino acids. [7] [8] MHC-β is a hexameric, asymmetric motor forming the bulk of the thick filament in cardiac muscle.MHC-β is composed of N-terminal globular heads (20 nm) that project laterally, and alpha helical tails (130 nm) that dimerize and multimerize into a coiled-coil motif to form the light meromyosin (LMM), thick filament rod. [9]

  4. Muscular dystrophy - Wikipedia

    en.wikipedia.org/wiki/Muscular_Dystrophy

    The person normally leads a normal life with some assistance. Rare cardiopulmonary complications can be life-threatening. [23] Myotonic muscular dystrophy: 160900 602668: DMPK CNBP: AD: Adulthood Skeletal muscles, heart, other muscle groups Presents with myotonia (delayed relaxation of muscles), as well as muscle wasting and weakness. [24]

  5. Stroke recovery - Wikipedia

    en.wikipedia.org/wiki/Stroke_recovery

    Around the same time, Brunnstrom also described the process of recovery, and divided the process into seven stages. As knowledge of the science of brain recovery improved, intervention strategies have evolved. Knowledge of strokes and the process of recovery after strokes has developed significantly in the late 20th century and early 21st century.

  6. Myosin - Wikipedia

    en.wikipedia.org/wiki/Myosin

    The Myosin V motor head can be subdivided into the following ... State of myosin VI from PDB 2V26 before the power stroke [43] Myosin VI is an unconventional myosin ...

  7. Myotonic dystrophy - Wikipedia

    en.wikipedia.org/wiki/Myotonic_dystrophy

    Life expectancy in non-congenital late-onset or adult onset DM1 is in the early 50s, [5] with pulmonary complications being the leading cause of death, followed by cardiac complications. [27] DM2 life expectancy has yet to be studied.

  8. MYH9 - Wikipedia

    en.wikipedia.org/wiki/MYH9

    Myosin-9 also known as myosin, heavy chain 9, non-muscle or non-muscle myosin heavy chain IIa (NMMHC-IIA) is a protein which in humans is encoded by the MYH9 gene. [5] [6]Non-muscle myosin IIA (NM IIA) is expressed in most cells and tissues where it participates in a variety of processes requiring contractile force, such as cytokinesis, cell migration, polarization and adhesion, maintenance of ...

  9. Sliding filament theory - Wikipedia

    en.wikipedia.org/wiki/Sliding_filament_theory

    Cross-bridge theory states that actin and myosin form a protein complex (classically called actomyosin) by attachment of myosin head on the actin filament, thereby forming a sort of cross-bridge between the two filaments. The sliding filament theory is a widely accepted explanation of the mechanism that underlies muscle contraction.

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