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  2. Thrombophilia - Wikipedia

    en.wikipedia.org/wiki/Thrombophilia

    The coagulation system, often described as a "cascade", consists of a group of proteins that interact in the formation of a fibrin-rich clot. Thrombosis is a multifactorial problem because there are often multiple reasons why a person might develop thrombosis.

  3. Coagulopathy - Wikipedia

    en.wikipedia.org/wiki/Coagulopathy

    Coagulopathy (also called a bleeding disorder) is a condition in which the blood's ability to coagulate (form clots) is impaired. [1] This condition can cause a tendency toward prolonged or excessive bleeding ( bleeding diathesis ), which may occur spontaneously or following an injury or medical and dental procedures.

  4. Antiphospholipid syndrome - Wikipedia

    en.wikipedia.org/wiki/Antiphospholipid_syndrome

    Antiphospholipid syndrome is known for causing arterial or venous blood clots, in any organ system, and pregnancy-related complications.While blood clots and pregnancy complications are the most common and diagnostic symptoms associated with APS, other organs and body parts may be affected like platelet levels, heart, kidneys, brain, and skin.

  5. Thrombocythemia - Wikipedia

    en.wikipedia.org/wiki/Thrombocythemia

    Reactive thrombocythemia is the most common cause of a high platelet count. It accounts for 88% to 97% of thrombocythemia cases in adults, and near 100% in children. In adults, acute infection, tissue damage, chronic inflammation and malignancy are the common causes of reactive thrombocythemia. Usually, one or more of these conditions is ...

  6. Coagulation - Wikipedia

    en.wikipedia.org/wiki/Coagulation

    Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The process of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of ...

  7. Thromboelastometry - Wikipedia

    en.wikipedia.org/wiki/Thromboelastometry

    The result is influenced by coagulation factors, platelets, fibrinogen and heparin. Low molecular weight heparin is detected at higher concentrations. [15] [16] In the absence of heparin, INTEM is a screening test for the haemostasis system. It is used for therapeutic decisions regarding the administration of fresh frozen plasma, coagulation ...

  8. Thrombotic thrombocytopenic purpura - Wikipedia

    en.wikipedia.org/wiki/Thrombotic...

    Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that results in blood clots forming in small blood vessels throughout the body. [2] This results in a low platelet count, low red blood cells due to their breakdown, and often kidney, heart, and brain dysfunction. [1]

  9. Congenital hypofibrinogenemia - Wikipedia

    en.wikipedia.org/wiki/Congenital_hypofibrinogenemia

    Congenital hypofibrinogenemia must be distinguished from: a) congenital afibrinogenemia, a rare disorder in which blood fibrinogen levels are either exceedingly low or undetectable due to mutations in both fibrinogen genes; b) congenital hypodysfibrinogenemia, a rare disorder in which one or more genetic mutations cause low levels of blood ...