Search results
Results from the WOW.Com Content Network
Sacubitril/valsartan, sold under the brand name Entresto among others, is a fixed-dose combination medication for use in heart failure. It consists of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan .
The term 'inhibitor' is often used in a general sense to describe any compound used to prevent unwanted polymerisation, however these compounds are often divided into 'retarders' and 'true inhibitors'. A true inhibitor has a well defined induction period during which no noticeable polymerisation takes place. They are consumed during this period ...
If the problem is a simple factor deficiency, mixing the patient plasma 1:1 with plasma that contains 100% of the normal factor level results in a level ≥50% in the mixture (say the patient has an activity of 0%; the average of 100% + 0% = 50%). [3] The PT or PTT will be normal (the mixing study shows correction).
A thermal shift assay (TSA) measures changes in the thermal denaturation temperature and hence stability of a protein under varying conditions such as variations in drug concentration, buffer formulation (pH or ionic strength), redox potential, or sequence mutation. The most common method for measuring protein thermal shifts is differential ...
PP2 is a substance that has frequently been used in cancer research as a "selective" inhibitor for Src-family kinases.It strongly inhibits the kinases Lck (IC 50 =4 nM), Fyn (5 nM) and Hck (5 nM), shows weaker inhibition of EGFR (480 nM) and practically no inhibition of ZAP-70 (100 μM) and JAK2 (50 μM).
The Fujifilm X100 is a series of digital compact cameras with a fixed prime lens. Originally part of the FinePix line, then becoming a member of the X series from Fujifilm , the X100 series includes the FinePix X100 , X100S , X100T , X100F , X100V , and X100VI .
The AMX-30 AuF1 is a French self-propelled gun vehicle currently in use by the armies of France and Saudi Arabia.It replaced the former Mk F3 155mm in French Army service. The AuF1 primary advantage is that it incorporates full armor and nuclear-biological-chemical protection for its crew of four, while the former Mk F3 155mm offered no protection and could carry only two of its four crew members.
The KPV was a heavy machine gun developed by S. V. Vladimirov. It was developed in 1944 and adopted in 1949. It combines the rate of fire of a heavy machine gun with the armor-piercing capabilities of antitank rifles and was designed to combat lightly armored targets, firepower and manpower of the enemy located behind light cover, as well as to be an anti-aircraft machine gun.