Search results
Results from the WOW.Com Content Network
www.schrodinger.com /products /glide Glide is a molecular modeling software for docking of small molecules into proteins and other biopolymers . [ 1 ] [ 2 ] It was developed by Schrödinger, Inc.
Macromolecular docking is the computational modelling of the quaternary structure of complexes formed by two or more interacting biological macromolecules. Protein –protein complexes are the most commonly attempted targets of such modelling, followed by protein– nucleic acid complexes.
During the course of the docking process, the ligand and the protein adjust their conformation to achieve an overall "best-fit" and this kind of conformational adjustment resulting in the overall binding is referred to as "induced-fit". [5] Molecular docking research focuses on computationally simulating the molecular recognition process.
This model quantified the nature of retrieval from long-term memory and characterized recall as a memory search with cycles of sampling and recovery. [8] In 1984, another quantum step forward occurred, when the theory was extended to recognition memory, in which a decision is based on summed activation of related memory traces. [ 9 ]
www.schrodinger.com /products /macromodel MacroModel is a computer program for molecular modelling of organic compounds and biopolymers . It features various chemistry force fields , plus energy minimizing algorithms, to predict geometry and relative conformational energies of molecules . [ 1 ]
Continuous spontaneous localization (CSL) model: [10] The Schrödinger equation is supplemented with a nonlinear and stochastic diffusion process driven by a suitably chosen universal noise coupled to the mass-density of the system, which counteracts the quantum spread of the wave function. As for the GRW model, the larger the system, the ...
The Atkinson–Shiffrin model (also known as the multi-store model or modal model) is a model of memory proposed in 1968 by Richard Atkinson and Richard Shiffrin. [1] The model asserts that human memory has three separate components: a sensory register, where sensory information enters memory,
The FitzHugh–Nagumo model (FHN) describes a prototype of an excitable system (e.g., a neuron). It is an example of a relaxation oscillator because, if the external stimulus I ext {\displaystyle I_{\text{ext}}} exceeds a certain threshold value, the system will exhibit a characteristic excursion in phase space , before the variables v ...