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Melanocytes are melanin-producing neural crest-derived [3] cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), [4] the inner ear, [5] vaginal epithelium, [6] meninges, [7] bones, [8] and heart found in many mammals and birds. [9] Melanin is a dark pigment primarily responsible ...
The pseudopodial process (aka the tanning process) happens slowly in dermal melanocytes in response to ultraviolet light and to production of new melanosomes and increased donation of melanosomes to adjacent keratinocytes, which are typical skin surface cells. Donation occurs when some keratinocytes engulf the end of the melanocyte pseudopodia ...
The neural crest is a ridge-like structure that is formed transiently between the epidermal ectoderm and neural plate during vertebrate development. Neural crest cells originate from this structure through the epithelial-mesenchymal transition, and in turn give rise to a diverse cell lineage—including melanocytes, craniofacial cartilage and bone, smooth muscle, dentin, peripheral and enteric ...
A pseudopod or pseudopodium (pl.: pseudopods or pseudopodia) is a temporary arm-like projection of a eukaryotic cell membrane that is emerged in the direction of movement. Filled with cytoplasm , pseudopodia primarily consist of actin filaments and may also contain microtubules and intermediate filaments .
MCH is a cyclic 19-amino acid neuropeptide, as it is a polypeptide chain that is able to act as a neurotransmitter.MCH neurons are mainly concentrated in the lateral hypothalamic area, zona incerta, and the incerto-hypothalamic area, but they are also located, in much smaller amounts, in the paramedian pontine reticular formation (PPRF), medial preoptic area, laterodorsal tegmental nucleus ...
the eye on the opposite side (the contralateral eye) sends information to layers 1, 4 and 6. This description applies to the LGN of many primates, but not all. The sequence of layers receiving information from the ipsilateral and contralateral (opposite side of the head) eyes is different in the tarsier . [ 10 ]
Brodmann area 6 is a cytoarchitecturally defined portion of the frontal lobe of the guenon.Brodmann-1909 regarded it as topographically and cytoarchitecturally homologous to the human agranular frontal area 6 and noted that, in the monkey, area 4 is larger than area 6, whereas, in the human, area 6 is larger than area 4.
The paramedian pontine reticular formation (PMPRF) is involved in coordinating horizontal conjugate eye movements and saccades. To do so, besides projecting to the ibsilateral abducens nucleus, the PMPRF projects fibers through the MLF to the contralateral oculomotor nucleus (specifically, those of its motor neurons that innervate the medial rectus muscle).