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Dementia, however, can present early in its disease course with depressive symptoms, meaning that this association could actually be reflecting that dementia causes late life depression. [23] Studies that have directly tried to determine whether depression is an independent risk factor for dementia have led to inconclusive results.
The onset of major depressive episodes or MDD often occurs in people in their mid-20s and less often in those over 65. The prevalence of depressive symptoms in the elderly is around 1–2%. [35] Elderly persons in nursing homes may have increased rates, up to 15–25%. [35]
The diagnostic criteria for depression in Alzheimer disease specify that it requires only 3 of the possible symptoms for major depressive disorder (MDD), rather than the 5 required to diagnose MDD itself, and the symptoms may fluctuate. Therefore, dAD often goes unrecognized within the spectrum of symptoms of Alzheimer's disease. [4]
The Food and Drug Administration (FDA) recently approved the nasal spray Spravato for the treatment of major depression in people who have not responded to at least two oral antidepressants.
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
Depression is a mental state of low mood and aversion to activity. [3] It affects about 3.5% of the global population, or about 280 million people worldwide, as of 2020. [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5]
In bipolar disorder, a mixed state is an episode during which symptoms of both mania and depression occur simultaneously. [49] Individuals experiencing a mixed state may have manic symptoms such as grandiose thoughts while simultaneously experiencing depressive symptoms such as excessive guilt or feeling suicidal. [49]
When younger people are prejudiced against the elderly and then become old themselves, their anti-elderly prejudice turns inward, causing depression. "People with more negative age stereotypes will likely have higher rates of depression as they get older." [88] Old age depression results in the 65+ population having the highest suicide rate.
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