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The use of ketamine as part of a "post-clubbing experience" has also been documented. [36] Ketamine's rise in the dance culture was most rapid in Hong Kong by the end of the 1990s. [32] Ketamine use as a recreational drug has been implicated in deaths globally, with more than 90 deaths in England and Wales in the years of 2005–2013. [37]
You may have also heard of ketamine therapy, which uses ketamine, a drug that was originally used as an animal anesthetic, administered in a clinical setting to improve mental health symptoms.
Prescriptions for ketamine have soared in recent years, driven by for-profit clinics and telehealth services offering the medication as a treatment for pain, depression, anxiety and other conditions.
Ketamine was first synthesized in 1962 by Calvin L. Stevens, [19] a professor of chemistry at Wayne State University and a Parke-Davis consultant. It was known by the developmental code name CI-581. [19] After promising preclinical research in animals, ketamine was tested in human prisoners in 1964. [31]
The researchers looked at data on 424 people with treatment-resistant depression who were treated between November 2017 and May 2021 at three ketamine infusion clinics in Virginia that specialize ...
Dennis S. Charney is an American biological psychiatrist and researcher, with expertise in the neurobiology and treatment of mood and anxiety disorders. [1] He is the author of Neurobiology of Mental Illness, The Physician's Guide to Depression and Bipolar Disorders and Molecular Biology for the Clinician, as well as the author of over 600 original papers and chapters.
Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10][12] is the S (+) enantiomer of ketamine. [5][13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression. Esketamine is the active enantiomer of ketamine in terms of ...
A closely related version, nasal esketamine, is licensed but has not been approved for routine NHS use, mainly because of cost. What is ketamine therapy and why is it used?