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[5] [6] This compound is a stimulant laxative and increases peristalsis in the gut. [5] [7] Sodium picosulfate is typically prescribed in a combined formulation with magnesium citrate, an osmotic laxative. This combination is a highly effective laxative, often prescribed to patients for bowel cleansing prior to colonoscopies. [5] [8]
Castor oil has been used orally to relieve constipation or to evacuate the bowel before intestinal surgery. [12] The laxative effect of castor oil is attributed to ricinoleic acid, which is produced by hydrolysis in the small intestine. [12] Use of castor oil for simple constipation is medically discouraged because it may cause violent diarrhea ...
While castor oil does contain many nutrients that may be beneficial for health, the U.S. Food and Drug Administration only approves castor oil for one use: as a stimulant laxative, per the ...
(In fact, the FDA has even approved the use of castor oil as an oral stimulative laxative, though it’s not recommended as a first-line treatment due to side effects like cramping.)
Prolonged use of stimulant laxatives can create drug dependence by damaging the colon's haustral folds, making users less able to move feces through their colon on their own. A study of patients with chronic constipation found that 28% of chronic stimulant laxative users lost haustral folds over the course of one year, while none of the control ...
Because most people, like yourself, dread the laxative prep and sedation, not to mention the procedure itself. But a colonoscopy is not your only option for screening for colon cancer.
Frequent use of enemas can cause laxative dependency. [67] The enema tube and solution may stimulate the vagus nerve, which may trigger an arrhythmia such as bradycardia. Enemas should not be used if there is an undiagnosed abdominal pain since the peristalsis of the bowel can cause an inflamed appendix to rupture.
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