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  2. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    This metabolite also has an affinity for the PDE receptors, about 40% of that of sildenafil. Thus, the metabolite is responsible for about 20% of sildenafil's action. Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) and to a lesser extent in the urine (around 13% of the administered oral dose).

  3. How to Take Viagra for Best Results - AOL

    www.aol.com/viagra-best-results-105700318.html

    Viagra works best when it’s taken at least 30 to 60 minutes before intimacy (and no more than four hours before). Eating food that’s high in fat can slow absorption and make Viagra work ...

  4. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) typically start working within 30 to 60 minutes, while avanafil (Stendra) works within 15 to 30 minutes. As with most prescription ...

  5. What Happens If You Take Viagra and You Don't Need It? - AOL

    www.aol.com/happens-viagra-dont-105800158.html

    In many of these studies, the researchers found more than 10 percent of men having intimacy with men used sildenafil citrate — and that its use is associated with higher risks of unprotected ...

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  7. How Much Viagra Is Too Much? - AOL

    www.aol.com/much-viagra-too-much-105700581.html

    Whether you use sildenafil or Viagra, take a 100-milligram sildenafil dose or a 20-milligram sildenafil dose, the effects of sildenafil won’t just get you hard when you don’t want to. The drug ...

  8. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

    www.aol.com/viagra-treats-side-effects-plus...

    A single tablet of sildenafil can do that — typically, one dose is all that’s required to produce a firmer, longer-lasting hardness. Studies have shown a 70 to 80 percent success rate in ...

  9. 5 Must-Know Tips Before Taking Sildenafil 100mg - AOL

    www.aol.com/5-must-know-tips-taking-105700758.html

    How Effective is Sildenafil 100mg? Sildenafil works well for most men with ED at any dosage, although the highest 100mg dosage produces improvements for a greater percentage of men than 50mg or 25mg.

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