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Those who travel to countries with poor sanitation should receive a live attenuated typhoid vaccine—Ty21a (Vivotif), which, in addition to the protection against typhoid fever, may provide some protection against paratyphoid fever caused by the S. enterica serotypes A and B. [4] In particular, a reanalysis of data from a trial conducted in ...
Typhoid fever, also known simply as typhoid, is a disease caused by Salmonella enterica serotype Typhi bacteria, also called Salmonella Typhi. [2] [3] Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. [4] [5] Often there is a gradual onset of a high fever over several days. [4]
In 2000, typhoid fever caused an estimated 21.7 million illnesses and 217,000 deaths. [1] It occurs most often in children and young adults between 5 and 19 years old. [2] In 2013, it resulted in about 161,000 deaths – down from 181,000 in 1990. [3]
Typhoid fever is caused by the bacterium Salmonella enterica Serovar Typhi. [ 37 ] In Canada alone, the typhus epidemic of 1847 killed more than 20,000 people from 1847 to 1848, mainly Irish immigrants in fever sheds and other forms of quarantine, who had contracted the disease aboard the crowded coffin ships in fleeing the Great Irish Famine .
Enteric fever is a medical term encompassing two types of salmonellosis, which, specifically, are typhoid fever and paratyphoid fever. [1] Enteric fever is a potentially life-threatening acute febrile systemic infection and is diagnosed by isolating a pathogen on culture.
The 1937 Croydon typhoid outbreak, also known as the Croydon epidemic of typhoid fever, [1] was an outbreak of typhoid fever in Croydon, Surrey, now part of London, in 1937. It resulted in 341 cases of typhoid (43 fatal), and it caused considerable local discontent leading to a media campaign and a public inquiry.
In 1964, there was an outbreak of typhoid in the city of Aberdeen, Scotland.The first two cases were identified on 20 May 1964; eventually over 400 cases were diagnosed and the patients were quarantined at the City Hospital in Urquhart Road, Woodend Hospital in Eday Road, and Tor-na-Dee Hospital in Milltimber which was used as an overflow hospital for typhoid cases. [1]
The chlorination of public drinking water led to the sharp reduction of typhoid in developed nations. [8] In typhoid-endemic countries, Typhoid vaccines have been shown to prevent 40 to 90% of cases during the first two years, [ 9 ] and may have some effect for up to seven years.