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  2. Schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Schizophrenia

    The question of how schizophrenia could be primarily genetically influenced, given that people with schizophrenia have lower fertility rates, is a paradox. It is expected that genetic variants that increase the risk of schizophrenia would be selected against, due to their negative effects on reproductive fitness .

  3. Causes of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Causes_of_schizophrenia

    The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.

  4. Hippocampus - Wikipedia

    en.wikipedia.org/wiki/Hippocampus

    MRI studies have found a smaller brain volume and larger ventricles in people with schizophrenia – however researchers do not know if the shrinkage is from the schizophrenia or from the medication. [155] [156] The hippocampus and thalamus have been shown to be reduced in volume; and the volume of the globus pallidus is increased. Cortical ...

  5. Hypofrontality - Wikipedia

    en.wikipedia.org/wiki/Hypofrontality

    Schizophrenia is a mental disorder that most commonly affects social and emotional functioning. Besides emotional and psychological influences, it is believed that genetics and early development play a role in the onset of schizophrenia. [8] The physical aspects of the disease are actual differences in the brain of the affected.

  6. IBM's AI can predict schizophrenia by looking at the brain's ...

    www.aol.com/news/2017-07-20-ibms-ai-can-predict...

    Schizophrenia is not a particularly common mental health disorder in America, affecting just 1.2 percent of the population (around 3.2 million people), but its effects can be debilitating.

  7. Neuropil - Wikipedia

    en.wikipedia.org/wiki/Neuropil

    The formula predicted an optimal brain with 3/5 (60%) of its volume occupied by neuropil. Experimental evidence taken from three mouse brains agrees with this result. The "fraction of wire is 0.59 ± 0.036 for layer IV of visual cortex, 0.62 ± 0.055 for layer Ib of piriform cortex, and 0.54 ± 0.035 for the stratum radiatum of hippocampal ...

  8. Adult neurogenesis - Wikipedia

    en.wikipedia.org/wiki/Adult_neurogenesis

    Studies suggest that people with schizophrenia have a reduced hippocampus volume, which is believed to be caused by a reduction of adult neurogenesis. Correspondingly, this phenomenon might be the underlying cause of many of the symptoms of the disease.

  9. Schizophrenia In America - The Huffington Post

    highline.huffingtonpost.com/articles/en/stop-the...

    This is one of the main reasons that 40 percent of people with schizophrenia stop taking their medications within 18 months. And while antipsychotics can help schizophrenia’s “positive” symptoms, such as hallucinations, they have a minimal impact on the “negative” symptoms, which are arguably more devastating.

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