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The positive predictive value (PPV), or precision, is defined as = + = where a "true positive" is the event that the test makes a positive prediction, and the subject has a positive result under the gold standard, and a "false positive" is the event that the test makes a positive prediction, and the subject has a negative result under the gold standard.
In a classification task, the precision for a class is the number of true positives (i.e. the number of items correctly labelled as belonging to the positive class) divided by the total number of elements labelled as belonging to the positive class (i.e. the sum of true positives and false positives, which are items incorrectly labelled as belonging to the class).
Precision and recall. In statistical analysis of binary classification and information retrieval systems, the F-score or F-measure is a measure of predictive performance. It is calculated from the precision and recall of the test, where the precision is the number of true positive results divided by the number of all samples predicted to be positive, including those not identified correctly ...
Phi value analysis assumes Hammond's postulate, which states that energy and chemical structure are correlated.Though the relationship between the folding intermediate and native state's structures may correlate that between their energies when the energy landscape has a well-defined, deep global minimum, free energy destabilizations may not give useful structural information when the energy ...
Predictive value of tests is the probability of a target condition given by the result of a test, [1] often in regard to medical tests.. In cases where binary classification can be applied to the test results, such yes versus no, test target (such as a substance, symptom or sign) being present versus absent, or either a positive or negative test), then each of the two outcomes has a separate ...
The q-value can be interpreted as the false discovery rate (FDR): the proportion of false positives among all positive results. Given a set of test statistics and their associated q-values, rejecting the null hypothesis for all tests whose q-value is less than or equal to some threshold ensures that the expected value of the false discovery rate is .
This expect-value is the product of the number of tests and the p-value. The q-value is the analog of the p-value with respect to the positive false discovery rate. [50] It is used in multiple hypothesis testing to maintain statistical power while minimizing the false positive rate. [51]
The weighted harmonic mean of p-values , …, is defined as = = = /, where , …, are weights that must sum to one, i.e. = =.Equal weights may be chosen, in which case = /.. In general, interpreting the HMP directly as a p-value is anti-conservative, meaning that the false positive rate is higher than expected.