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Elderly rodents typically die of cancer or kidney disease, but not of cardiovascular disease. In humans, the relative incidence of cancer increases exponentially with age for most cancers, but levels off or may even decline by age 60–75 [ 3 ] (although colon / rectal cancer continues to increase).
Alzheimer's disease (AD) is a neurodegenerative disease and the most common cause of dementia; it usually occurs in old age. Familial Alzheimer's disease (FAD or EOFAD for early onset) is an inherited and uncommon form of AD. Familial AD usually strikes earlier in life, defined as before the age of 65.
A guiding mnemonic commonly used by geriatricians in the United States and Canada is the 5 M's of Geriatrics which describes mind, mobility, multicomplexity, medications and matters most to elicit patient values. [6] It is common for elderly adults to be managing multiple long-term conditions (multimorbidity). Age-associated changes in ...
The two most common chronic conditions in the elderly are high blood pressure and arthritis, with diabetes, coronary heart disease, and cancer also being reported among the elder population. [ 16 ] In examining the statistics of chronic disease among the living elderly, it is also important to make note of the statistics pertaining to ...
Degenerative disease is the result of a continuous process based on degenerative cell changes, affecting tissues or organs, which will increasingly deteriorate over time. [ 1 ] In neurodegenerative diseases , cells of the central nervous system stop working or die via neurodegeneration .
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. [2] It is the cause of 60–70% of cases of dementia. [2] [15] The most common early symptom is difficulty in remembering recent events. [1]
It is the most common neurodegenerative disease. [1] Even with billions of dollars being used to find a treatment for Alzheimer's disease, no effective treatments have been found. [15] Within clinical trials stable and effective AD therapeutic strategies have a 99.5% failure rate. [16]
[160] [166] Changing from a youth-focused culture to having a more positive attitude towards aging and being more respectful of seniors like Japan can help elderly Americans extend their life span and live out their sunset years in dignity. American society will have to confront the negative stereotypes of aging and ageism. [166]