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Lugol's iodine is a liquid made up of two parts potassium iodide for every one part elemental iodine in water. [8] Lugol's iodine was first made in 1829 by the French physician Jean Lugol. [7] [8] It is on the World Health Organization's List of Essential Medicines. [9] [10] Lugol's iodine is available as a generic medication and over the ...
Purified water is 50 mL and the balance is alcohol. This 7% tincture solution is about 3.5 times more concentrated than USP 2% tincture. [citation needed] As in the case of Lugol's iodine, the role of iodide in the solution is to increase the solubility of the elemental iodine, by turning it to the soluble triiodide anion I 3 −. However ...
[17] [16] Potassium iodide can be administered as tablets or as Lugol's iodine solution. [16] The same dosage is recommended by the US Food and Drug Administration. [18] A single daily dose is typically sufficient for 24-hour protection. [16] However, in cases of prolonged or repeated exposure, health authorities may recommend multiple daily ...
Wrong timing of iodine use may even increase the risk by triggering the Plummer effect. [10] The Plummer effect is, however, helpful in the management of thyrotoxicosis, where the usage of Lugol’s solution helps to limit the release of thyroid hormones into the bloodstream. [4]
Tincture of iodine: iodine in ethanol, or iodine and sodium iodide in a mixture of ethanol and water. Lugol's iodine: iodine and iodide in water alone, forming mostly triiodide. Unlike tincture of iodine, Lugol's iodine has a minimised amount of the free iodine (I 2) component. Iodine glycerin, a preparation used in dentistry.
Jean Guillaume Auguste Lugol. Jean Guillaume Auguste Lugol (18 August 1786 – 16 September 1851) was a French physician. Lugol was born in Montauban. He studied medicine in Paris and graduated with a medical degree in 1812. In 1819, he was appointed acting physician at the Hôpital Saint-Louis, a post he held until he retired.
Lugol's iodine contains potassium iodide and a stoichiometric amount of elemental iodine, so that significant amounts of triiodide ion exist in this solution. Tincture of iodine, although nominally a solution of elemental iodine in ethanol, also contains significant amounts of triiodide, due to its content of both iodide and water.
Guidelines recommend the administration of inorganic iodide (potassium iodide or Lugol's iodine [6] [21]) to reduce the synthesis and release of thyroid hormone. In high dosage, iodine may reduce the synthesis of thyroid hormone via the Wolff–Chaikoff effect and its release via the Plummer effect. [5]
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