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Most initial symptoms of leukemia are related to problems with the bone-marrow function. There are a variety of symptoms that children may experience. The symptoms tend to appear quickly in acute leukemia and slowly over time in chronic leukemia. [1] Symptoms in the different types of childhood leukemia include: feelings of fatigue or weakness
Specialty: Hematology and oncology: Symptoms: Bleeding, bruising, fatigue, fever, increased risk of infections [2] Usual onset: All ages, [3] most common in 60s and 70s. [4] It is the most common malignant cancer in children, but the cure rates are also higher for them.
Juvenile myelomonocytic leukemia (JMML) is a rare form of chronic leukemia (cancer of the blood) that affects children, commonly those aged four and younger. [2] The name JMML now encompasses all diagnoses formerly referred to as juvenile chronic myeloid leukemia (JCML), chronic myelomonocytic leukemia of infancy, and infantile monosomy 7 syndrome.
In childhood, T-cell acute lymphoblastic leukemia (T-ALL) patients can expect a 5-year event-free survival (EFS) rate of 70% and an overall survival (OS) rate of 80%. [1] Among the approximately 25% of children who relapse, survival rates drop to 30-50%, with patients generally showing a much poorer prognosis. [1]
Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [1] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [1]
Chronic lymphocytic leukemia; Other names: B-cell chronic lymphocytic leukemia (B-CLL) [1] Peripheral blood smear showing CLL cells: Specialty: Hematology and oncology: Symptoms: Early: None [2] Later: Non-painful lymph nodes swelling, feeling tired, fever, weight loss, night sweats [2] Usual onset: Older than 50 [3] Risk factors
Haematopoiesis. The two lineages of myeloid and lymphoid cells are formed from haematopoietic stem cells. Leukemia subtypes are categorised into single clinical entities so that they can be diagnosed and treated appropriately. Leukaemias are subdivided into lymphoid and myeloid neoplasms, depending on which bone marrow cells are cancerous. The ...
Swollen gums due to infiltration by leukemia cells in a person with AML. Most signs and symptoms of AML are caused by the crowding out in bone marrow of space for normal blood cells to develop. [7] A lack of normal white blood cell production makes people more susceptible to infections. [8]