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The Draize test is an acute toxicity test devised in 1944 by Food and Drug Administration (FDA) toxicologists John H. Draize and Jacob M. Spines. Initially used for testing cosmetics, the procedure involves applying 0.5 mL or 0.5 g of a test substance to the eye or skin of a restrained, conscious animal, and then leaving it for a set amount of time before rinsing it out and recording its effects.
"Typically, animal tests for cosmetics include skin and eye irritation tests where chemicals are rubbed onto the shaved skin or dripped into the eyes of rabbits; repeated oral force-feeding studies lasting weeks or months to look for signs of general illness or specific health hazards, such as cancer or birth defects; and even widely condemned ...
Stanford bunny: 1993-94 [11] Greg Turk, Marc Levoy at Stanford University: Ceramic rabbit [12] 69,451 triangles [11] Figurine of unknown authorship and licensing status, scan itself released under a two-clause BSD license. A test of range scanning physical objects. Originally .ply file. Stanford dragon: 1996 [11] Stanford University: Chinese ...
Botulinum toxin therapy of strabismus is a medical technique used sometimes in the management of strabismus, in which botulinum toxin is injected into selected extraocular muscles in order to reduce the misalignment of the eyes. The injection of the toxin to treat strabismus, reported upon in 1981, is considered to be the first ever use of ...
Care must be taken when testing the menace response. Waving an object close to an animal's eyes or face does not necessarily demonstrate a functioning menace response, in part because the animal can sense such objects and react to them via senses other than sight.
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There are two basic types of microinjection systems. The first is called a constant flow system and the second is called a pulsed flow system.In a constant flow system, which is relatively simple and inexpensive though clumsy and outdated, a constant flow of a sample is delivered from a micropipette and the amount of the sample which is injected is determined by how long the needle remains in ...
Optography is the process of viewing or retrieving an optogram, an image on the retina of the eye. A belief that the eye "recorded" the last image seen before death was widespread in the late 19th and early 20th centuries, and was a frequent plot device in fiction of the time, to the extent that police photographed the victims' eyes in several ...