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Cartilage is composed of specialized cells called chondrocytes that produce a large amount of collagenous extracellular matrix, abundant ground substance that is rich in proteoglycan and elastin fibers. Cartilage is classified into three types — elastic cartilage, hyaline cartilage, and fibrocartilage — which differ in their relative ...
Hyaline cartilage is the most common kind of cartilage in the human body. [2] It is primarily composed of type II collagen and proteoglycans. [2] Hyaline cartilage is located in the trachea, nose, epiphyseal plate, sternum, and ribs. [2] Hyaline cartilage is covered externally by a fibrous membrane known as the perichondrium. [2]
It is found in tendons, skin, artery walls, cornea, the endomysium surrounding muscle fibers, fibrocartilage, and the organic part of bones and teeth. COL1A1, COL1A2: Osteogenesis imperfecta, Ehlers–Danlos syndrome, infantile cortical hyperostosis a.k.a. Caffey's disease II: Hyaline cartilage, makes up 50% of all cartilage protein.
Thick elastic fibers from the visceral pleura (outer lining) of the human lung. Elastic fibers are found in the skin, lungs, arteries, veins, connective tissue proper, elastic cartilage, periodontal ligament, fetal tissue and other tissues which must undergo mechanical stretching. [1] In the lung there are thick and thin elastic fibers. [3]
Isogenous groups differentiate into individual chondrocytes where they continue to produce and deposit extracellular matrix (ECM), lengthening the cartilage and increasing its diameter. [3] [5] This is termed interstitial growth and is one of only two ways cartilage can grow. [4] Cartoon representation of hyaline cartilage with isogenous groups.
Perichondrium can be found around the perimeter of elastic cartilage and hyaline cartilage. Perichondrium is a type of irregular collagenous ordinary connective tissue, and also functions in the growth and repair of cartilage. Perichondrium contains type I collagen [1] and type XII collagen. [2]
In the deeper zones, chondrocytes form columns that are oriented perpendicular to the cartilage surface, along with the collagen fibers. Different behaviors may be exhibited by chondrocytes depending on their position within the different layers. In primary chondrocyte cultures, these zonal differences in synthetic properties may persist.
Elastic cartilage, fibroelastic cartilage or yellow fibrocartilage [1] is a type of cartilage present in the pinnae (auricles) of the ear giving it shape, [2] provides shape for the lateral region of the external auditory meatus, [3] medial part of the auditory canal [3] Eustachian tube, corniculate and cuneiform laryneal cartilages, [3] and the epiglottis.