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Cancer slope factors (CSF) are used to estimate the risk of cancer associated with exposure to a carcinogenic or potentially carcinogenic substance. A slope factor is an upper bound, approximating a 95% confidence limit , on the increased cancer risk from a lifetime exposure to an agent by ingestion or inhalation .
Tobacco is the greatest single cause of oral and pharyngeal cancer. Using tobacco increases the risk of oral cancer by 3 to 6 times [20] [9] and is responsible for around 40% of all oral cancers. [21] Smokeless tobacco (including chewing tobacco, snuff, snus) also causes oral cancer. [22] [23] [24] Cigar and pipe smoking are also important risk ...
Dipping tobacco is a cause of oral cancer, oesophagus cancer, and pancreas cancer. [19] Increased risk of oral cancer caused by dipping tobacco is present in countries such as the United States but particularly prevalent in Southeast Asian countries where the use of smokeless tobacco is common. [20] [21]
“Excessive chewing can lead to problems with the joint of the jaw, known as temporomandibular joint dysfunction (TMD),” Gary Liu, a board-certified pediatric dentist, cautions.
Chewing tobacco is a cause of oral cancer, oesophagus cancer, and pancreas cancer. [20] Increased risk of oral cancer caused by chewing tobacco is present in countries such as the United States but particularly prevalent in Southeast Asian countries where the use of smokeless tobacco is common. [21] [22] All tobacco products, including chewing ...
Smokeless tobacco (including products where tobacco is chewed) is a cause of oral cancer, oesophagus cancer, and pancreas cancer. [5] Increased risk of oral cancer caused by smokeless tobacco is present in countries such as the United States but particularly prevalent in Southeast Asian countries where the use of smokeless tobacco is common ...
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