Search results
Results from the WOW.Com Content Network
Lamotrigine, sold under the brand name Lamictal among others, is a medication used to treat epilepsy and stabilize mood in bipolar disorder. [ 5 ] [ 8 ] For epilepsy, this includes focal seizures , tonic-clonic seizures , and seizures in Lennox-Gastaut syndrome . [ 8 ]
[96] [97] On the other hand, evidence is conflicting for carbamazepine regarding any increased risk of congenital physical anomalies or neurodevelopmental disorders by intrauterine exposure. [96] Similarly, children exposed lamotrigine or phenytoin in the womb do not seem to differ in their skills compared to those who were exposed to ...
In general, contraindications to antipsychotic switching are cases in which the risk of switching outweighs the potential benefit. Contraindications to antipsychotic switching include effective treatment of an acute psychotic episode, patients stable on a LAI antipsychotic with a history of poor adherence, and stable patients with a history of self-injurious behavior, violent behavior, or ...
Lamotrigine exposure appears to carry a relatively low risk of adverse neurodevelopmental outcomes. Levetiracetam also carries a low risk, based on more limited data. The data on carbamazepine are mixed but generally suggest a low risk. The data on topiramate are more mixed and suggest negative effects.
Switching directly is usually only a safe option for switching between certain SSRIs and SNRIs with short half-lives, as these medications are less likely to cause drug interactions or unwanted ...
Carbamazepine, an anticonvulsant drug, was also developed, which was authorized by numerous regulatory organisations worldwide. Since 2000, different antipsychotic drugs have had their antimanic indications authorised by FDA. They include olanzapine, risperidone, quetiapine, ziprasidone, aripiprazole, etc.
[150] [151] Controlled release carbamazepine appears to work as well as immediate release carbamazepine, and may have fewer side effects. [152] [153] In the United Kingdom, carbamazepine or lamotrigine are recommended as first-line treatment for focal seizures, with levetiracetam and valproate as second-line due to issues of cost and side effects.
Carbamazepine was the first anti-convulsant shown to be effective for treating bipolar mania. It has not been extensively studied in bipolar depression. [2] It is generally considered a second-line agent due to its side effect profile. [2] Lamotrigine is considered a first-line agent for the treatment of bipolar depression.