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  2. Action potential - Wikipedia

    en.wikipedia.org/wiki/Action_potential

    An action potential occurs when the membrane potential of a specific cell rapidly rises and falls. [1] This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of excitable cells, which include animal cells like neurons and muscle cells, as well as some plant cells.

  3. Refractory period (physiology) - Wikipedia

    en.wikipedia.org/wiki/Refractory_period_(physiology)

    The relative refractory period immediately follows the absolute. As voltage-gated potassium channels open to terminate the action potential by repolarizing the membrane, the potassium conductance of the membrane increases dramatically. K + ions moving out of the cell bring the membrane potential closer to the equilibrium potential for potassium ...

  4. Presynaptic inhibition - Wikipedia

    en.wikipedia.org/wiki/Presynaptic_inhibition

    Presynaptic inhibition is a phenomenon in which an inhibitory neuron provides synaptic input to the axon of another neuron (axo-axonal synapse) to make it less likely to fire an action potential. Presynaptic inhibition occurs when an inhibitory neurotransmitter, like GABA, acts on GABA receptors on the axon terminal.

  5. Cardiac action potential - Wikipedia

    en.wikipedia.org/wiki/Cardiac_action_potential

    The slope of phase 0 on the action potential waveform (see figure 2) represents the maximum rate of voltage change of the cardiac action potential and is known as dV/dt max. In pacemaker cells (e.g. sinoatrial node cells ), however, the increase in membrane voltage is mainly due to activation of L-type calcium channels.

  6. Afterhyperpolarization - Wikipedia

    en.wikipedia.org/wiki/Afterhyperpolarization

    Afterhyperpolarization, or AHP, is the hyperpolarizing phase of a neuron's action potential where the cell's membrane potential falls below the normal resting potential. This is also commonly referred to as an action potential's undershoot phase. AHPs have been segregated into "fast", "medium", and "slow" components that appear to have distinct ...

  7. Summation (neurophysiology) - Wikipedia

    en.wikipedia.org/wiki/Summation_(neurophysiology)

    Basic ways that neurons can interact with each other when converting input to output. Summation, which includes both spatial summation and temporal summation, is the process that determines whether or not an action potential will be generated by the combined effects of excitatory and inhibitory signals, both from multiple simultaneous inputs (spatial summation), and from repeated inputs ...

  8. Depolarization - Wikipedia

    en.wikipedia.org/wiki/Depolarization

    During an action potential, the depolarization is so large that the potential difference across the cell membrane briefly reverses polarity, with the inside of the cell becoming positively charged. The change in charge typically occurs due to an influx of sodium ions into a cell, although it can be mediated by an influx of any kind of cation or ...

  9. Pacemaker potential - Wikipedia

    en.wikipedia.org/wiki/Pacemaker_potential

    The slope determines the time taken to reach the threshold potential, and thus the timing of the next action potential. [ 2 ] In a healthy sinoatrial node (SAN, a complex tissue within the right atrium containing pacemaker cells that normally determine the intrinsic firing rate for the entire heart [ 3 ] [ 4 ] ), the pacemaker potential is the ...