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The Draize test is an acute toxicity test devised in 1944 by Food and Drug Administration (FDA) toxicologists John H. Draize and Jacob M. Spines. Initially used for testing cosmetics, the procedure involves applying 0.5 mL or 0.5 g of a test substance to the eye or skin of a restrained, conscious animal, and then leaving it for a set amount of time before rinsing it out and recording its effects.
"Typically, animal tests for cosmetics include skin and eye irritation tests where chemicals are rubbed onto the shaved skin or dripped into the eyes of rabbits; repeated oral force-feeding studies lasting weeks or months to look for signs of general illness or specific health hazards, such as cancer or birth defects; and even widely condemned ...
Ralph is a rabbit. Speaking with Humane Society International for a documentary, he talks about his life as a "tester" for cosmetic products.Ralph tells the production crew how he is blind in one eye, partially deaf and has chemical burns on his back that are still tender and sting if he breathes or moves a certain way.
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One of Wilhelm Kühne's rabbit optograms from 1878. The window the rabbit was facing appears to be discernible in the image. Optography is the process of viewing or retrieving an optogram, an image on the retina of the eye. A belief that the eye "recorded" the last image seen before death was widespread in the late 19th and early 20th centuries ...
Wild rabbit with inflammation of eyes and nose caused by myxomatosis (Germany). Myxoma virus is in the genus Leporipoxvirus (family Poxviridae; subfamily Chordopoxvirinae). Like other poxviruses, myxoma viruses are large DNA viruses with linear double-stranded DNA. Virus replication occurs in the cytoplasm of the cell.
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It causes thick firm debris to form in the ear canal, and can eventually migrate to the skin of the outer ear and face. Symptoms include scratching and shaking of the head. Treatment includes topical selamectin, or injections of ivermectin and frequent cleanings of the rabbit's environment.