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This adjustability is important for their application in drug delivery system in which the functional parameters need to be precisely controlled. [8] Preliminary studies indicate that antibiotics and anticancer drugs may be encapsulated in electrospun nanofibers by adding the drug into the polymer solution prior to electrospinning.
A drug carrier or drug vehicle is a substrate used in the process of drug delivery which serves to improve the selectivity, effectiveness, and/or safety of drug administration. [1] Drug carriers are primarily used to control the release of drugs into systemic circulation.
Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. The modern form of a drug delivery system should minimize side-effects and reduce both dosage and dosage frequency. Recently, nanoparticles have aroused attention due to their potential ...
Melt blowing is a conventional fabrication method of micro- and nanofibers where a polymer melt is extruded through small nozzles surrounded by high speed blowing gas. The randomly deposited fibers form a nonwoven sheet product applicable for filtration, sorbents, apparels and drug delivery systems.
Electrospinning is a fiber production method that uses electrical force (based on electrohydrodynamic [1] principles) to draw charged threads of polymer solutions for producing nanofibers with diameters ranging from nanometers to micrometers.
The conventional drug delivery system is the absorption of the drug across a biological membrane, whereas the targeted release system releases the drug in a dosage form. The advantages to the targeted release system is the reduction in the frequency of the dosages taken by the patient, having a more uniform effect of the drug, reduction of drug ...
Conversely, many new medical technologies involving nanoparticles as delivery systems or as sensors would be examples of nanobiotechnology since they involve using nanotechnology to advance the goals of biology. The definitions enumerated above will be utilized whenever a distinction between nanobio and bionano is made in this article.
[1] [2] These nanofibers have been shown to detect various gaseous chemicals, such as hydrogen chloride (HCl), ammonia (NH 3), Hydrazine (N 2 H 4), chloroform (CHCl 3), and methanol (CH 3 OH). [1] PANI nanofibers can be further fined-tuned by doping and modifying the polymer chain conformation, among other methods, to increase selectivity to ...