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This adjustability is important for their application in drug delivery system in which the functional parameters need to be precisely controlled. [8] Preliminary studies indicate that antibiotics and anticancer drugs may be encapsulated in electrospun nanofibers by adding the drug into the polymer solution prior to electrospinning.
Nanocarriers are useful in the drug delivery process because they can deliver drugs to site-specific targets, allowing drugs to be delivered in certain organs or cells but not in others. Site-specificity is a major therapeutic benefit as it prevents drugs from being delivered to the wrong places.
Rod or tube-like, rather than nearly spherical, nanocarriers may offer additional advantages in terms of drug delivery systems. Such drug carrier particles possess additional choice of the axial ratio , the curvature, and the "all-sweeping" hydrodynamic-related rotation , and they can be modified chemically at the inner surface, the outer ...
Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. The modern form of a drug delivery system should minimize side-effects and reduce both dosage and dosage frequency. Recently, nanoparticles have aroused attention due to their potential ...
Electrospinning is a fiber production method that uses electrical force (based on Electrohydrodynamic [1] principals) to draw charged threads of polymer solutions for producing nanofibers with diameters ranging from nanometers to micrometers.
A drug carrier or drug vehicle is a substrate used in the process of drug delivery which serves to improve the selectivity, effectiveness, and/or safety of drug administration. [1] Drug carriers are primarily used to control the release of drugs into systemic circulation.
Nanofabrics research is an interdisciplinary effort involving bioengineering, [5] molecular chemistry, physics, electrical engineering, computer science, and systems engineering. [3] Applications of nanofabrics have the potential to revolutionize textile manufacturing [6] and areas of medicine such as drug delivery and tissue engineering. [7]
A range of polymeric nanocomposites are used for biomedical applications such as tissue engineering, drug delivery, cellular therapies. [29] [30] Due to unique interactions between polymer and nanoparticles, a range of property combinations can be engineered to mimic native tissue structure and properties. A range of natural and synthetic ...