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  2. Progesterone receptor - Wikipedia

    en.wikipedia.org/wiki/Progesterone_receptor

    The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. It is activated by the steroid hormone progesterone . In humans, PR is encoded by a single PGR gene residing on chromosome 11q 22, [ 5 ] [ 6 ] [ 7 ] it has two isoforms, PR-A and PR-B , that differ in their ...

  3. Selective progesterone receptor modulator - Wikipedia

    en.wikipedia.org/wiki/Selective_progesterone...

    A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor (PR), the biological target of progestogens like progesterone.A characteristic that distinguishes such substances from full receptor agonists (e.g., progesterone, progestins) and full antagonists (e.g., aglepristone) is that their action differs in different tissues, i.e. agonist in some ...

  4. Progestogen (medication) - Wikipedia

    en.wikipedia.org/wiki/Progestogen_(medication)

    Certain progestogens are used to support pregnancy, including progesterone, hydroxyprogesterone caproate, dydrogesterone, and allylestrenol. They are used questionably for treatment of recurrent pregnancy loss and for prevention of preterm birth in pregnant women with a history of at least one spontaneous preterm birth. [42]

  5. Progesterone (medication) - Wikipedia

    en.wikipedia.org/wiki/Progesterone_(medication)

    Progesterone (P4), sold under the brand name Prometrium among others, is a medication and naturally occurring steroid hormone. [20] It is a progestogen and is used in combination with estrogens mainly in hormone therapy for menopausal symptoms and low sex hormone levels in women.

  6. Progestogen - Wikipedia

    en.wikipedia.org/wiki/Progestogen

    The main biological role of progestogens in the body is in the female reproductive system, and the male reproductive system, [19] with involvement in regulation of the menstrual cycle, maintenance of pregnancy, and preparation of the mammary glands for lactation and breastfeeding following parturition in women; in men progesterone affects ...

  7. Medroxyprogesterone acetate - Wikipedia

    en.wikipedia.org/wiki/Medroxyprogesterone_acetate

    Progesterone, via transformation into neurosteroids such as 5α-dihydroprogesterone, 5β-dihydroprogesterone, allopregnanolone, and pregnanolone (catalyzed by the enzymes 5α-and 5β-reductase and 3α- and 3β-HSD), is a positive allosteric modulator of the GABA A receptor, and is associated with a variety of effects mediated by this property ...

  8. Pregnancy hormones - Wikipedia

    en.wikipedia.org/wiki/Pregnancy_hormones

    Receptor levels rise as individuals age among certain ethnic groups, and typically, white women have greater receptor levels compared to black or Japanese women. [40] It has been hypothesized that the absence of a tumor-suppressor gene may lead to the inability to decrease the activity of estrogen receptors when cells enter the cell cycle or ...

  9. Etonogestrel - Wikipedia

    en.wikipedia.org/wiki/Etonogestrel

    Etonogestrel is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. [16] It works by stopping ovulation , thickening the mucus around the opening of the cervix , and altering the lining of the uterus . [ 17 ]

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