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However, vaginal rings have the potential to provide long-term controlled release of microbicide drugs. Long-acting formulations, like vaginal rings, are potentially advantageous since they could be easy to use, requiring replacement only once a month. This ease of use could prove very important to make sure that products are used properly.
Phosphine is an attractive fumigant because it is lethal to insects and rodents, but degrades to phosphoric acid, which is non-toxic. As sources of phosphine, for farm use, pellets of aluminium phosphide (AlP), calcium phosphide (Ca 3 P 2), or zinc phosphide (Zn 3 P 2) are used. These phosphides release phosphine upon contact with atmospheric ...
The “Shug” was a noninjectable device consisting of 2 silicone plugs with nylon tails to help anchor the plug to the vas deferens, and was inserted via the no-scalpel scrotal puncture method. [288] Injectable medical polyurethane was used as a vas-occlusive contraceptive for several hundred thousand men in China in the 1980s. [289] [142]
Administering a vaginal tablet without an applicator. Intravaginal administration is a route of administration where the substance is applied inside the vagina . Pharmacologically , it has the potential advantage to result in effects primarily in the vagina or nearby structures (such as the vaginal portion of cervix ) with limited systemic ...
Phosgene is an organic chemical compound with the formula COCl 2. It is a toxic, colorless gas; in low concentrations, its musty odor resembles that of freshly cut hay or grass. [ 7 ] It can be thought of chemically as the double acyl chloride analog of carbonic acid , or structurally as formaldehyde with the hydrogen atoms replaced by chlorine ...
Tributylphosphine is the organophosphorus compound with the chemical formula P(CH 2 CH 2 CH 2 CH 3) 3, often abbreviated as PBu 3. It is a tertiary phosphine. It is an oily liquid at room temperature, with a nauseating odor. It reacts slowly with atmospheric oxygen, and rapidly with other oxidizing agents, to give tributylphosphine oxide.
[1] [81] Contraceptive vaginal rings and contraceptive patches likewise have been found to increase SHBG levels by 2.5-fold and 3.5-fold, respectively. [ 125 ] [ 81 ] Birth control pills containing high doses of ethinylestradiol (>50 μg) can increase SHBG levels by 5- to 10-fold, which is similar to the increase that occurs during pregnancy ...
LiiP(C 6 H 5) 2 + CH 3 I → CH 3 P(C 6 H 5) 2 + LiI. Phosphine is a precursor to some tertiary phosphines by hydrophosphination of alkenes. For example, in the presence of basic catalysts PH 3 adds of Michael acceptors such as acrylonitrile: [7] PH 3 + 3 CH 2 =CHZ → P(CH 2 CH 2 Z) 3 (Z = NO 2, CN, C(O)NH 2)