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Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and men. [13] It is also being studied for other types of cancer. [13] It has been used for Albright syndrome. [14] Tamoxifen is typically taken daily by mouth for five years for breast cancer. [14]
Clomifene successfully induced ovulation in subfertile women and on February 1, 1967, it was approved in the US for the treatment of ovulation dysfunction in women who were trying to conceive. [5] Toxicological issues prevented long term use of clomifene and further drug development for other potential applications such as breast cancer ...
Toremifene is the generic name of the drug and its INN Tooltip International Nonproprietary Name and BAN Tooltip British Approved Name, while toremifene citrate is its USAN Tooltip United States Adopted Name and JAN Tooltip Japanese Accepted Name and torémifène is its DCF Tooltip Dénomination Commune Française. [42] [43] [44] [45]
The advisory from US Surgeon General Vivek Murthy says the "majority of Americans are unaware of this risk" that leads to about 100,000 cases of cancer and 20,000 deaths annually in the US.
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WASHINGTON (Reuters) -The United States issued sanctions against a Russian judge on Tuesday for her role in the detention of human-rights activist Alexei Gorinov over his opposition to Russia's ...
A dispute over the U.S. Food and Drug Administration's refusal to let two e-cigarette companies sell flavored vape products due to their health risk to youths goes before the U.S. Supreme Court on ...
N-Desmethyltamoxifen (developmental code name ICI-55,548) is a major metabolite of tamoxifen, a selective estrogen receptor modulator (SERM). [1] [2] N-Desmethyltamoxifen is further metabolized into endoxifen (4-hydroxy-N-desmethyltamoxifen), which is thought to be the major active form of tamoxifen in the body.