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The dental follicle, also known as dental sac, is made up of mesenchymal cells and fibres surrounding the enamel organ and dental papilla of a developing tooth. [1] It is a vascular fibrous sac [2] containing the developing tooth and its odontogenic organ. The dental follicle (DF) differentiates into the periodontal ligament.
The Hertwig epithelial root sheath (HERS) or epithelial root sheath is a proliferation of epithelial cells located at the cervical loop of the enamel organ in a developing tooth. Hertwig epithelial root sheath initiates the formation of dentin in the root of a tooth by causing the differentiation of odontoblasts from the dental papilla.
B: dental papilla C: dental follicle. The tooth germ is an aggregation of cells that eventually forms a tooth. [2] These cells are derived from the ectoderm of the first pharyngeal arch and the ectomesenchyme of the neural crest. [1] [3] [4] The tooth germ is organized into three parts: the enamel organ, the dental papilla and the dental sac or ...
The dental follicle → The ectomesenchymal cells which are part of the fibrous sac that have been formed; The dental papilla → The ectomesenchymal cells which are lying deep to the enamel organ; The enamel organ → purely the epithelial component; The tissues which have been derived from each of the three components are:
(1) The HERS, (2) epithelial rests of Malassez, (3) dental follicle, (4) cementoblasts, (5) periodontal ligament, (6) alveolar cells, (7) bone, (8) odontoblasts. In dentistry, the epithelial cell rests of Malassez (ERM) or epithelial rests of Malassez (pax epithelialis pediodontii) are part of the periodontal ligament cells around a tooth.
The tooth bud (sometimes called the tooth germ) is an aggregation of cells that eventually forms a tooth and is organized into three parts: the enamel organ, the dental papilla and the dental follicle. [3] The enamel organ is composed of the outer enamel epithelium, inner enamel epithelium, stellate reticulum and stratum intermedium. [3]
The radiographic distinction between an enlarged dental follicle and a small dentigerous cyst can be difficult and fairly arbitrary. Generally, any pericoronal radiolucency that is greater than 3–4 mm in diameter is considered suggestive of cyst formation. Some dentigerous cysts may result in considerable displacement of the involved tooth.
Tooth development begins at week 6 in utero, in the oral epithelium. The process is divided into three stages: Initiation; Morphogenesis and; Histogenesis [2]; At the end of week 7 i.u., localised proliferations of cells in the dental laminae form round and oval swellings known as tooth buds, which will eventually develop into mesenchymal cells and surround the enamel organ.