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The submucosa (or tela submucosa) is a thin layer of tissue in various organs of the gastrointestinal, respiratory, and genitourinary tracts. It is the layer of dense irregular connective tissue that supports the mucosa ( mucous membrane ) and joins it to the muscular layer , the bulk of overlying smooth muscle (fibers running circularly within ...
It is approximately 1.5 centimetres (5 ⁄ 8 inch) in diameter in newborns after 35 weeks of gestational age, [7] and 2.5–3 cm (1– 1 + 1 ⁄ 8 in) in diameter in adults. On abdominal X-rays , the small intestine is considered to be abnormally dilated when the diameter exceeds 3 cm. [ 8 ] [ 9 ] On CT scans , a diameter of over 2.5 cm is ...
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus.The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines.
From the inner cavity of the gut (the lumen) outwards, these are the mucosa, the submucosa, the muscular layer and the serosa or adventitia. The mucosa is the innermost layer of the gastrointestinal tract. It surrounds the lumen of the tract and comes into direct contact with digested food .
In 1996, the number of cases were estimated around 2.5 million worldwide but there is no population-base data as it is not notifiable disease. In India, the prevalence is estimated 0.2–2.3% in males and 1.2–4.6% in females; with age range of 11 to 60 years. It is widely reported in South Asian diaspora in Europe, North America and South Africa.
Around 800 to 1,000 minor salivary glands are located throughout the oral cavity within the submucosa [12] of the oral mucosa in the tissue of the buccal, labial, and lingual mucosa, the soft palate, the lateral parts of the hard palate, and the floor of the mouth or between muscle fibers of the tongue. [13]
The gut-associated lymphoid tissue lies throughout the intestine, covering an area of approximately 260–300 m 2. [5] In order to increase the surface area for absorption, the intestinal mucosa is made up of finger-like projections (), covered by a monolayer of epithelial cells, which separates the GALT from the lumen intestine and its contents.
The submucosa consists of a dense and irregular layer of connective tissue with blood vessels, lymphatics, and nerves branching into the mucosa and muscular layer. It contains the submucous plexus , and enteric nervous plexus , situated on the inner surface of the muscular layer.