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140,000 (2021) [9] Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. [10] An epileptic seizure is the clinical manifestation of an abnormal, excessive, and synchronized electrical discharge in the neurons. [1] The occurrence of two or more unprovoked seizures defines epilepsy. [11]
Dravet syndrome (DS), previously known as severe myoclonic epilepsy of infancy (SMEI), is an autosomal dominant genetic disorder which causes a catastrophic form of epilepsy, with prolonged seizures that are often triggered by hot temperatures or fever. [1] It is very difficult to treat with anticonvulsant medications.
In 1957 he described the hemiconvulsion-hemiplegia-epilepsy(HHE) syndrome, [5] in 1961 [6] and 1966 [7] the Lennox-Gastaut syndrome, and in 1981 [8] and 1982 [9] the late variant of the benign childhood epilepsy with occipital paroxysms. After the Second World War he was influential in reactivating the International League Against Epilepsy ...
Lennox–Gastaut syndrome (LGS) is a complex, rare, and severe childhood-onset epilepsy syndrome. It is characterized by multiple and concurrent seizure types including tonic seizure, cognitive dysfunction, and slow spike waves on electroencephalogram (EEG), which are very abnormal. [1] Typically, it presents in children aged 3–5 years and ...
Viktor K. Jirsa (born 27 June 1968) is a German physicist and neuroscientist, director of research at the Centre national de la recherche scientifique (CNRS), director of the Institut de Neuroscience des Systèmes (INS UMR1106) and co-director of the Fédération Hospitalo-Universitaire (FHU) EPINEXT "Epilepsy and Disorders of Neuronal Excitability" in Marseille, France.
Thomas N. Seyfried (born 1946 [1]) is an American professor of biology, genetics, and biochemistry at Boston College. He received his PhD from the University of Illinois Urbana-Champaign in 1976. His postdoctoral fellowship studies were in the Department of Neurology at the Yale University School of Medicine where he served as an assistant ...
Frequency. ~10% of people (overall worldwide lifetime risk) [10][11] A seizure is a sudden change in behavior, movement, and/or consciousness due to abnormal electrical activity in the brain. [3][6] Seizures can look different in different people.
Epilepsy is a neurological condition of recurrent episodes of unprovoked epileptic seizures. A seizure is an abnormal neuronal brain activity that can cause intellectual, emotional, and social consequences. Epilepsy affects children and adults of all ages and races, and is one of the most common neurological disorders of the nervous system. [1]