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  2. Suzetrigine - Wikipedia

    en.wikipedia.org/wiki/Suzetrigine

    Suzetrigine (developmental code name VX-548) is a non- opioid, small-molecule analgesic that works as a selective inhibitor of Na v 1.8 -dependent pain-signaling pathways in the peripheral nervous system. [1][2] It is being developed by Vertex Pharmaceuticals and has completed two phase 3 clinical trials. [1][3] Vertex Pharmaceuticals announced ...

  3. Peripheral neuropathy - Wikipedia

    en.wikipedia.org/wiki/Peripheral_neuropathy

    Shooting pain, numbness, tingling, tremors, bladder problems, unsteadiness. Peripheral neuropathy, often shortened to neuropathy, refers to damage or disease affecting the nerves. [1] Damage to nerves may impair sensation, movement, gland function, and/or organ function depending on which nerve fibers are affected.

  4. Neuropathic pain - Wikipedia

    en.wikipedia.org/wiki/Neuropathic_pain

    4.1%-12.4% (12-month prevalence, US adults) [1] Neuropathic pain is pain caused by a lesion or disease of the somatosensory nervous system. [2][3] Neuropathic pain may be associated with abnormal sensations called dysesthesia or pain from normally non-painful stimuli (allodynia). It may have continuous and/or episodic (paroxysmal) components.

  5. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat partial seizures and neuropathic pain. [7][10] It is a commonly used medication for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central pain. [11]

  6. Pain management - Wikipedia

    en.wikipedia.org/wiki/Pain_management

    Image of visual pain. Pain management is an aspect of medicine and health care involving relief of pain (pain relief, analgesia, pain control) in various dimensions, from acute and simple to chronic and challenging. Most physicians and other health professionals provide some pain control in the normal course of their practice, and for the more ...

  7. Diabetic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Diabetic_neuropathy

    It is usually described as a glove-stocking distribution of numbness, sensory loss, dysesthesia and nighttime pain. The pain can feel like burning, pricking sensation, achy or dull. A pins and needles sensation is common. Loss of proprioception, the sense of where a limb is in space, is affected early.

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