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Additional researched vinca alkaloids include vincaminol, vineridine, and vinburnine. Vinpocetine is a semi-synthetic derivative of vincamine (sometimes described as "a synthetic ethyl ester of apovincamine"). [14] Minor vinca alkaloids include minovincine, methoxyminovincine, minovincinine, vincadifformine, desoxyvincaminol, and vincamajine ...
It is a source of the drugs vincristine and vinblastine, used to treat cancer. [3] It was formerly included in the genus Vinca as Vinca rosea. It has many vernacular names among which are arivotaombelona or rivotambelona, tonga, tongatse or trongatse, tsimatiririnina, and vonenina. [4]
Vinca difformis in habitat, Cáceres, Spain. Vinca plants are subshrubs or herbaceous, and have slender trailing stems 1–2 m (3 + 1 ⁄ 2 – 6 + 1 ⁄ 2 ft) long but not growing more than 20–70 cm (8– 27 + 1 ⁄ 2 in) above ground; the stems frequently take root where they touch the ground, enabling the plant to spread widely.
Serratiopeptidase (Serratia E-15 protease, also known as serralysin, serrapeptase, serratiapeptase, serratia peptidase, serratio peptidase, or serrapeptidase) is a proteolytic enzyme (protease) produced by enterobacterium Serratia sp. E-15, now known as Serratia marcescens ATCC 21074. [1]
Catharanthus roseus, known formerly as Vinca rosea, is a main source of vinca alkaloids, now sometimes called catharanthus alkaloids. The plant produces about 130 of these compounds, including vinblastine and vincristine , two drugs used to treat cancer.
Vindesine, also termed Eldisine, is a semisynthetic vinca alkaloid derived from the flowering plant Catharanthus roseus. [1] Like the natural (e.g. vinblastine and vincristine) and semisynthetic vinca alkaloids (e.g. vinorelbine and vinflunine) derived from this plant, vindesine is an inhibitor of mitosis that is used as a chemotherapy drug. [2]
Tissue plasminogen activator (TPA) is a serine protease occurring in animals including humans. Human-identical TPA (produced industrially by genetically recombinant microorganisms) has an established medical use in the treatment of ischemic stroke: by its proteolytic activity it enables the action of another enzyme (plasmin), which breaks down the protein (fibrin) of blood clots.
Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor (lesser periwinkle), comprising about 25–65% of its indole alkaloids by weight. It can also be synthesized from related alkaloids. [1]
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