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  2. Discovery and development of ACE inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    This yielded a potent inhibitor that was 1000 times more potent than succinyl-L-proline. [3] [7] The optimal acyl chain length for mercapto alkanoyl derivates of proline was found to be 3-mercaptopropanoyl-L-proline, 5 times greater than that of 2-mercaptoalkanoyl derivates and 50 times greater than that of 4-mercaptoalkanoyl derivates. So the ...

  3. Metoprolol - Wikipedia

    en.wikipedia.org/wiki/Metoprolol

    Metoprolol, sold under the brand name Lopressor among others, is a medication used to treat angina and a number of conditions involving an abnormally fast heart rate. [4] It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines. [4] It is a selective β 1 receptor blocker ...

  4. ACE inhibitor - Wikipedia

    en.wikipedia.org/wiki/ACE_inhibitor

    Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. [ 1 ] [ 2 ] This class of medicine works by causing relaxation of blood vessels as well as a decrease in blood volume , which leads to lower blood pressure and decreased oxygen demand ...

  5. List of abbreviations used in medical prescriptions - Wikipedia

    en.wikipedia.org/wiki/List_of_abbreviations_used...

    3 times a day t.i.d., t.d. ter in die: 3 times a day AMA style avoids use of this abbreviation (spell out "3 times a day") tinct. tinctura: tincture t.i.w. 3 times a week mistaken for "twice a week" top. topical TPN total parenteral nutrition tr, tinc., tinct. tinctura: tincture trit. triturate: grind to a powder troch. trochiscus: lozenge tsp

  6. Discovery and development of beta-blockers - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Figure 1: The chemical structure of dichloroisoprenaline or dichloroisoproterenol (), abbreviated DCI — the first β-blocker to be developed. β adrenergic receptor antagonists (also called beta-blockers or β-blockers) were initially developed in the 1960s, for the treatment of angina pectoris but are now also used for hypertension, congestive heart failure and certain arrhythmias. [1]

  7. Lisinopril - Wikipedia

    en.wikipedia.org/wiki/Lisinopril

    Lisinopril is a medication belonging to the drug class of angiotensin-converting enzyme (ACE) inhibitors and is used to treat hypertension (high blood pressure), heart failure, and heart attacks. [7] For high blood pressure it is usually a first-line treatment. It is also used to prevent kidney problems in people with diabetes mellitus. [7]

  8. Fosinopril - Wikipedia

    en.wikipedia.org/wiki/Fosinopril

    Fosinopril is an angiotensin converting enzyme (ACE) inhibitor [2] used for the treatment of hypertension and some types of chronic heart failure. Fosinopril is the only phosphonate-containing ACE inhibitor marketed, by Bristol-Myers Squibb under the trade name Monopril. Fosinopril is a cascading pro-drug.

  9. Long-acting beta-adrenoceptor agonist - Wikipedia

    en.wikipedia.org/wiki/Long-acting_beta...

    They should not be used without an accompanying steroid due to an increased risk of severe symptoms, including exacerbation in both children and adults. [3] A 2018 meta-analysis was unable to determine whether an increase serious adverse events reported in the previous meta-analysis on regular salmeterol alone is abolished by the additional use ...

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