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  2. Hailey–Hailey disease - Wikipedia

    en.wikipedia.org/wiki/Hailey–Hailey_disease

    The cause of the disease is a haploinsufficiency of the enzyme ATP2C1; [7] the ATP2C1 gene is located on chromosome 3, which encodes the protein hSPCA1.A mutation on one copy of the gene causes only half of this necessary protein to be made and the cells of the skin do not adhere together properly due to malformation of intercellular desmosomes, causing acantholysis, blisters and rashes.

  3. Pemphigus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Pemphigus_erythematosus

    Pemphigus erythematosus (Senear-Usher Syndrome) is a rare form of pemphigus with features of pemphigus foliaceus and lupus erythematosus. [ 1 ] [ 2 ] It was first described by Francis Senear and Barney Usher at the University of Illinois College of Medicine in 1926. [ 3 ]

  4. Paraneoplastic pemphigus - Wikipedia

    en.wikipedia.org/wiki/Paraneoplastic_pemphigus

    Paraneoplastic pemphigus (PNP) is an autoimmune disorder stemming from an underlying tumor. It is hypothesized that antigens associated with the tumor trigger an immune response resulting in blistering of the skin and mucous membranes .

  5. Pemphigus - Wikipedia

    en.wikipedia.org/wiki/Pemphigus

    The tissue is skin from a patient with Pemphigus vulgaris. Note the intercellular IgG deposits in the epidermis and the early intraepidermal vesicle caused by acantholysis. Pemphigus (/ ˈ p ɛ m f ɪ ɡ ə s / or / p ɛ m ˈ f aɪ ɡ ə s /) is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes. [1]

  6. Pemphigus vulgaris - Wikipedia

    en.wikipedia.org/wiki/Pemphigus_vulgaris

    Pemphigus vulgaris is a rare chronic blistering skin disease and the most common form of pemphigus.Pemphigus was derived from the Greek word pemphix, meaning blister. [1] It is classified as a type II hypersensitivity reaction in which antibodies are formed against desmosomes, components of the skin that function to keep certain layers of skin bound to each other.

  7. 'Bachelor' Joey Graziadei reveals what causes his eyes to ...

    www.aol.com/news/bachelor-joey-graziadei-reveals...

    Graziadei said that the whites of his eyes can sometimes look jaundiced, or more yellow, as a result of the condition. He said it tends to impact him more when he is worn out. "I am healthy.

  8. Pseudoexfoliation syndrome - Wikipedia

    en.wikipedia.org/wiki/Pseudoexfoliation_syndrome

    Pseudoexfoliation syndrome, often abbreviated as PEX [1] and sometimes as PES or PXS, is an aging-related systemic disease manifesting itself primarily in the eyes which is characterized by the accumulation of microscopic granular amyloid-like protein fibers. [2] Its cause is unknown, although there is speculation that there may be a genetic ...

  9. Photopsia - Wikipedia

    en.wikipedia.org/wiki/Photopsia

    visual snow syndrome; Vitreous shrinkage or liquefaction, which is the most common cause of photopsia, causes a pull in vitreoretinal attachments, irritating the retina and causing it to discharge electrical impulses. These impulses are interpreted by the brain as flashes.

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